Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
F Leng, P Edison - Nature Reviews Neurology, 2021 - nature.com
Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
How COVID-19 affects the brain
M Boldrini, PD Canoll, RS Klein - JAMA psychiatry, 2021 - jamanetwork.com
COVID-19 has resulted in more than 120 million cases and 2.6 million deaths to date.
Respiratory and gastrointestinal symptoms are accompanied by short-and long-term …
Respiratory and gastrointestinal symptoms are accompanied by short-and long-term …
Negative feedback control of neuronal activity by microglia
Microglia, the brain's resident macrophages, help to regulate brain function by removing
dying neurons, pruning non-functional synapses, and producing ligands that support …
dying neurons, pruning non-functional synapses, and producing ligands that support …
Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease
D Bairamian, S Sha, N Rolhion, H Sokol… - Molecular …, 2022 - Springer
Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
Blood-brain barrier dysfunction amplifies the development of neuroinflammation: understanding of cellular events in brain microvascular endothelial cells for …
F Takata, S Nakagawa, J Matsumoto… - Frontiers in cellular …, 2021 - frontiersin.org
Neuroinflammation is involved in the onset or progression of various neurodegenerative
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
[PDF][PDF] Astrocyte crosstalk in CNS inflammation
M Linnerbauer, MA Wheeler, FJ Quintana - Neuron, 2020 - cell.com
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …
dependent dementia. There is currently no effective treatment for AD, which may be …
[PDF][PDF] Spatial transcriptomics and in situ sequencing to study Alzheimer's disease
Although complex inflammatory-like alterations are observed around the amyloid plaques of
Alzheimer's disease (AD), little is known about the molecular changes and cellular …
Alzheimer's disease (AD), little is known about the molecular changes and cellular …
[HTML][HTML] Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration
JV Andersen, KH Markussen, E Jakobsen… - …, 2021 - Elsevier
Glutamate is the primary excitatory neurotransmitter of the brain. Cellular homeostasis of
glutamate is of paramount importance for normal brain function and relies on an intricate …
glutamate is of paramount importance for normal brain function and relies on an intricate …