Tumor budding is a well-established independent prognostic factor in colorectal cancer but
a standardized method for its assessment has been lacking. The primary aim of the …

An international panel of multidisciplinary experts convened to develop recommendations
for managing patients with colorectal cancer (CRC) and synchronous liver metastases …

Background Induction of a clinical complete response with chemoradiotherapy, followed by
observation via a watch-and-wait approach, has emerged as a management option for …

Objective: The aim of the study was to confirm the noninferiority of mesorectal excision (ME)
alone to ME with lateral lymph node dissection (LLND) in terms of efficacy. Background …

Background & Aims Deep submucosal invasion (DSI) is considered a key risk factor for
lymph node metastasis (LNM) and important criterion to recommend surgery in T1 colorectal …

Background Although benefits of laparoscopic surgery compared with open surgery have
been suggested, the long-term survival of patients undergoing laparoscopic surgery for …

PURPOSE To provide expert guidance to clinicians and policymakers in resource-
constrained settings on the management of patients with late-stage colorectal cancer …

Purpose Trifluridine/tipiracil (TAS-102) was effective in patients with metastatic colorectal
cancer (mCRC) in a phase II Japanese trial. This regional trial evaluated the efficacy and …

Though the incidence of several cancers in Western societies is regulated wisely, some
cancers such as breast, lung, and colorectal cancer are currently rising in many low-and …

Objective This study was designed to estimate the clinical significance of the C-reactive
protein (CRP)/albumin ratio (CAR) for prediction of postoperative survival in patients with …