Metabolic effects of contraceptive steroids

R Sitruk-Ware, A Nath - Reviews in endocrine and metabolic disorders, 2011 - Springer
Estrogen and progestins have been used by millions of women as effective combined
contraceptives. The safety of hormonal contraceptives has been documented by years of …

Venous and arterial thrombosis during oral contraceptive use: risks and risk factors

BC Tanis, FR Rosendaal - Seminars in vascular medicine, 2003 - thieme-connect.com
Since the introduction of oral contraceptives, their use has been associated with an
increased risk of both venous and arterial thrombosis. Pulmonary embolism, myocardial …

Metformin Versus Ethinyl Estradiol-Cyproterone Acetate in the Treatment of Nonobese Women with Polycystic Ovary Syndrome: A Randomized Study

L Morin-Papunen, I Vauhkonen… - The Journal of …, 2003 - academic.oup.com
Metformin, an insulin-sensitizing drug, has been shown to improve ovarian function and
glucose metabolism in obese women with polycystic ovary syndrome (PCOS), but its effects …

Effects of oral and transvaginal ethinyl estradiol on hemostatic factors and hepatic proteins in a randomized, crossover study

R Sitruk-Ware, G Plu-Bureau, J Menard… - The Journal of …, 2007 - academic.oup.com
Context: The use of combined hormonal contraceptives with ethinyl estradiol (EE) and a
progestin results in alterations in potential biomarkers of venous thromboembolism risk …

Nestorone®/estradiol transdermal gel

R Sitruk-Ware, DNR Carrara, A Grenier - US Patent 9,682,087, 2017 - Google Patents
The invention discloses compositions and methods for ensuring in both women of fertile age
where it ensures also a contraception with additional health benefits and in postmenopausal …

Comparison of the impact of vaginal and oral administration of combined hormonal contraceptives on hepatic proteins sensitive to estrogen

RL Sitruk-Ware, J Menard, M Rad, J Burggraaf… - Contraception, 2007 - Elsevier
OBJECTIVE: We evaluated the effects of a new combined hormonal contraceptive vaginal
ring (CVR) delivering the nonandrogenic progestin Nestorone®(NES) and ethinyl estradiol …

An open-label, comparative study of the effects of a dose-reduced oral contraceptive containing 0.02 mg ethinylestradiol/2 mg chlormadinone acetate on hemostatic …

UH Winkler, P Röhm, K Höschen - Contraception, 2010 - Elsevier
OBJECTIVE: The study was conducted to compare the effects of 0.02 mg ethinylestradiol
(EE)/2 mg chlormadinone acetate (CMA), given for 24 days each cycle, with those of 0.02 …

The impact of oral contraceptives on cardiometabolic parameters

M Farahmand, F Ramezani Tehrani… - Journal of …, 2016 - Springer
Purpose There is much controversy regarding the use of oral contraceptive pills (OCPs) on
cardiometabolic parameters, which is why this longitudinal population-based study was …

[HTML][HTML] Decreased plasma sensitivity to activated protein C by oral contraceptives is associated with decreases in plasma glucosylceramide

H Deguchi, BN Bouma, S Middeldorp, YM Lee… - Journal of Thrombosis …, 2005 - Elsevier
Oral contraceptive (OC) use increases venous thrombosis (VTE) risk and causes activated
protein C (APC) resistance. Plasma glucosylceramide (GlcCer) deficiency is associated with …

Long-term oral contraceptive treatment, metabolic syndrome and measures of cardiovascular risk in pre-menopausal women: National Health and Nutrition …

BE Hurwitz, N Henry, RB Goldberg - Gynecological endocrinology, 2009 - Taylor & Francis
Aim. Differences in subclinical cardiometabolic measures were examined as a function of
oral contraceptive pills (OCP) treatment duration to compare never-treated women with four …