Meningiomas are the most common primary intracranial tumor. Important advances are
occurring in meningioma research. These are expected to accelerate, potentially leading to …

Meningiomas are the most common primary intracranial tumors. The majority of
meningiomas are benign, but they can present different grades of dedifferentiation from …

Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important
functions in the regulation of growth and survival of certain cell types during embryonal …

Background No proven effective medical therapy for surgery and radiation-refractory
meningiomas exists. Sunitinib malate (SU011248) is a small-molecule tyrosine kinase …

Purpose: Aggressive meningiomas that progress after surgery/radiotherapy represent an
unmet medical need. Strong and constant expression of SSTR2A receptors and activation of …

Background The outcomes of patients with surgery-and radiation-refractory meningiomas
treated with medical therapies are poorly defined. Published reports are limited by small …

Purpose Progesterone receptors are expressed in approximately 70% of meningiomas.
Mifepristone is an oral antiprogestational agent reported to have modest activity in a phase II …

Abstract Learning Objectives After completing this course, the reader will be able to:
Evaluate patients with grade II and III meningiomas for possible implementation of adjuvant …

Intracranial meningiomas are often indolent tumors which typically grow over years to
decades. Nonetheless, meningiomas that progress after maximum safe resection and …

Meningiomas are mostly benign, slow-growing tumors of the CNS that originate from
arachnoidal cap cells. While monosomy 22 is the most frequent genetic abnormality found in …