Oxidative stress in oocyte aging and female reproduction

L Wang, J Tang, L Wang, F Tan, H Song… - Journal of cellular …, 2021 - Wiley Online Library
In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …

Global distribution, toxicity to humans and animals, biodegradation, and nutritional mitigation of deoxynivalenol: A review

Y Tu, S Liu, P Cai, T Shan - … Reviews in Food Science and Food …, 2023 - Wiley Online Library
Deoxynivalenol (DON) is one of the main types of B trichothecenes, and it causes health‐
related issues in humans and animals and imposes considerable challenges to food and …

[HTML][HTML] Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply

H Zhang, C Li, D Wen, R Li, S Lu, R Xu, Y Tang, Y Sun… - Redox Biology, 2022 - Elsevier
In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos

YJ Niu, W Zhou, ZW Nie, KT Shin… - Journal of pineal …, 2020 - Wiley Online Library
Melatonin, a major hormone of the pineal gland, exerts many beneficial effects on
mitochondria. Several studies have shown that melatonin can protect against toxin‐induced …

Melatonin supplementation during in vitro maturation of oocyte enhances subsequent development of bovine cloned embryos

Q An, W Peng, Y Cheng, Z Lu, C Zhou… - Journal of cellular …, 2019 - Wiley Online Library
Oocyte quality, which is directly related to reprogramming competence, is a major important
limiting factor in animal cloning efficiency. Compared with oocytes matured in vivo, in vitro …

The toxicity mechanisms of DON to humans and animals and potential biological treatment strategies

S Hou, J Ma, Y Cheng, H Wang, J Sun… - Critical Reviews in Food …, 2023 - Taylor & Francis
Deoxynivalenol, also known as vomitotoxin, is produced by Fusarium, belonging to the
group B of the trichothecene family. DON is widely polluted, mainly polluting cereal crops …

Melatonin ameliorates ochratoxin A-induced oxidative stress and apoptosis in porcine oocytes

M Lan, Y Zhang, X Wan, MH Pan, Y Xu, SC Sun - Environmental Pollution, 2020 - Elsevier
Melatonin is a hormone which is generated from pineal gland, and it is responsible for the
regulation of wake-sleep cycle. Melatonin is a well-known antioxidant and free radical …

Deoxynivalenol induces testicular ferroptosis by regulating the Nrf2/System Xc−/GPX4 axis

X Yang, T Huang, Y Chen, F Chen, Y Liu… - Food and Chemical …, 2023 - Elsevier
Deoxynivalenol (DON) is the most common mycotoxin contaminant in food and feed. DON
accumulation in food chain severely threatens human and animal health due to the toxic …

[HTML][HTML] Melatonin: a potential regulator of DNA methylation

K Linowiecka, AT Slominski, RJ Reiter, M Böhm… - Antioxidants, 2023 - mdpi.com
The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular
processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to …

[HTML][HTML] Mitochondrial dysfunction in the offspring of obese mothers and it's transmission through damaged oocyte mitochondria: Integration of mechanisms

AL Elias-Lopez, O Vázquez-Mena… - Biochimica et Biophysica …, 2023 - Elsevier
In vivo and in vitro studies demonstrate that mitochondria in the oocyte, are susceptible to
damage by suboptimal pre/pregnancy conditions, such as obesity. These suboptimal …