Colorectal cancer (CRC) is a major cause of morbidity and mortality, being the third most
common cancer diagnosed in both men and women in the world. Several environmental …

All components of the gut are adversely impacted by critical illness. Gut injury can not only
propagate local damage, but can also cause distant injury and organ failure. Understanding …

The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and
intestinal secretions, prevents passage of luminal substances and antigens through the …

Infants born under 1,500 g have an increased incidence of necrotizing enterocolitis in the
ileum and the colon, which is a life-threatening intestinal necrosis. This is in part due to …

Dysbiosis of gut microbiota occurs in many human chronic immune-mediated diseases,
such as inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC) …

There is increasing concern in identifying the mechanisms underlying the intimate control of
the intestinal barrier, as deregulation of its function is strongly associated with digestive …

Probiotic as a preventive medicine is emerging as an indispensable tool in addressing the
foodborne infections or gastrointestinal disorders. The present study was sought to …

Tumor-associated macrophages (TAMs) are the main population of myeloid cells infiltrating
solid tumors and the pivotal orchestrators of cancer-promoting inflammation. However, due …

The Na+/H+ exchanger transporters (NHE) play an important role in various biologic
processes including Na+ absorption, intracellular pH homeostasis, cell volume regulation …

Background Bacterial translocation was observed in critical illness and patients with chronic
diseases such as liver cirrhosis and chronic kidney disease (CKD). Hypokalemia is a …