The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic'system?

NJ Abbott, ME Pizzo, JE Preston, D Janigro… - Acta …, 2018 - Springer
Brain fluids are rigidly regulated to provide stable environments for neuronal function, eg,
low K+, Ca 2+, and protein to optimise signalling and minimise neurotoxicity. At the same …

Brain–immune interactions and neuroinflammation after traumatic brain injury

V Dinet, KG Petry, J Badaut - Frontiers in neuroscience, 2019 - frontiersin.org
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …

[HTML][HTML] The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse …

NJ Sylvain, MM Salman, MJ Pushie, H Hou… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Stroke is the second leading cause of death and the third leading cause of disability
globally. Edema is a hallmark of stroke resulting from dysregulation of water homeostasis in …

TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types

Y Khalfallah, R Kuta, C Grasmuck, A Prat… - Scientific reports, 2018 - nature.com
Stress granules (SGs) are cytoplasmic foci that form in response to various external stimuli
and are essential to cell survival following stress. SGs are studied in several diseases …

Reversible lesion in the splenium of the corpus callosum

S Tetsuka - Brain and behavior, 2019 - Wiley Online Library
Abstract Aim of Review The presence of isolated, reversible lesions in the splenium of the
corpus callosum (SCC) is essential to confirm the diagnosis of mild encephalitis …

Astrocytes in functional recovery following central nervous system injuries

QM Alhadidi, GA Bahader, O Arvola… - The Journal of …, 2024 - Wiley Online Library
Astrocytes are increasingly recognised as partaking in complex homeostatic mechanisms
critical for regulating neuronal plasticity following central nervous system (CNS) insults …

Cytokine and growth factor activation in vivo and in vitro after spinal cord injury

E Garcia, J Aguilar-Cevallos… - Mediators of …, 2016 - Wiley Online Library
Spinal cord injury results in a life‐disrupting series of deleterious interconnected
mechanisms encompassed by the primary and secondary injury. These events are mediated …

Aquaporins in cancer biology

CS Moon, D Moon, SK Kang - Frontiers in oncology, 2022 - frontiersin.org
Aquaporins (AQPs) are a family of transmembrane water channel proteins, which were
initially characterized as a novel protein family that plays a vital role in transcellular and …

Neuroimmunological implications of AQP4 in astrocytes

H Ikeshima-Kataoka - International journal of molecular sciences, 2016 - mdpi.com
The brain has high-order functions and is composed of several kinds of cells, such as
neurons and glial cells. It is becoming clear that many kinds of neurodegenerative diseases …

Clinical relevance of brain atrophy assessment in multiple sclerosis. Implications for its use in a clinical routine

R Zivadinov, D Jakimovski, S Gandhi… - Expert review of …, 2016 - Taylor & Francis
Introduction: Brain atrophy measurement in multiple sclerosis (MS) has become an
important outcome for determining patients at risk for developing physical and cognitive …