The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome

Q Su, RI Lau, Q Liu, MKT Li, JWY Mak, W Lu, ISF Lau… - Cell Host & Microbe, 2024 - cell.com
The mechanisms underlying the many phenotypic manifestations of post-acute COVID-19
syndrome (PACS) are poorly understood. Herein, we characterized the gut microbiome in …

SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells

A Villacampa, E Alfaro, C Morales… - Cell Communication and …, 2024 - Springer
Background Hyperinflammation, hypercoagulation and endothelial injury are major findings
in acute and post-COVID-19. The SARS-CoV-2 S protein has been detected as an isolated …

Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults

SJ Russell, K Parker, A Lehoczki, D Lieberman… - GeroScience, 2024 - Springer
Long COVID, also known as PASC (post-acute sequelae of SARS-CoV-2), is a complex
infection-associated chronic condition affecting tens of millions of people worldwide. Many …

What is quality in long covid care? Lessons from a national quality improvement collaborative and multi-site ethnography

T Greenhalgh, JL Darbyshire, C Lee, E Ladds… - BMC medicine, 2024 - Springer
Background Long covid (post covid-19 condition) is a complex condition with diverse
manifestations, uncertain prognosis and wide variation in current approaches to …

Intrinsic factors behind long COVID: IV. Hypothetical roles of the SARS‐CoV‐2 nucleocapsid protein and its liquid–liquid phase separation

A Eltayeb, F Al‐Sarraj, M Alharbi… - Journal of Cellular …, 2024 - Wiley Online Library
When the SARS‐CoV‐2 virus infects humans, it leads to a condition called COVID‐19 that
has a wide spectrum of clinical manifestations, from no symptoms to acute respiratory …

[HTML][HTML] Predictors of non-recovery from fatigue and cognitive deficits after COVID-19: a prospective, longitudinal, population-based study

TJ Hartung, T Bahmer, I Chaplinskaya-Sobol… - …, 2024 - thelancet.com
Background Despite the high prevalence and major disability associated with fatigue and
cognitive deficits after SARS-CoV-2 infection, little is known about long-term trajectories of …

Post-Acute Sequelae of COVID-19 (PASC) in Pediatrics: Factors That Impact Symptom Severity and Referral to Treatment

CM Soprano, R Ngo, CA Konys, A Bazier, KS Salamon - Children, 2023 - mdpi.com
The post-acute sequelae of COVID-19 (PASC) is a complex condition. While there are
emerging studies on its effects in adults, there is scarce research regarding the long-term …

Single‐cell RNA sequencing reveals characteristics of myeloid cells in post-acute sequelae of SARS-CoV-2 patients with persistent respiratory symptoms

H Yoon, LS Dean, B Jiyarom, VS Khadka… - Frontiers in …, 2024 - frontiersin.org
Background Although our understanding of the immunopathology and subsequent risk and
severity of COVID-19 disease is evolving, a detailed account of immune responses that …

Long-Term Impairment of Working Ability in Subjects under 60 Years of Age Hospitalised for COVID-19 at 2 Years of Follow-Up: A Cross-Sectional Study

L Frallonardo, AI Ritacco, A Amendolara, D Cassano… - Viruses, 2024 - mdpi.com
Background: Coronavirus disease 2019 (COVID-19) can lead to persistent and debilitating
symptoms referred to as Post-Acute sequelae of SARS-CoV-2 infection (PASC) This broad …

High Prevalence of Long COVID in Common Variable Immunodeficiency: An Italian Multicentric Study

A Villa, C Milito, CM Deiana, RF Gambier… - Journal of Clinical …, 2024 - Springer
The long-term effects of SARS-CoV-2 infection represent a relevant global health problem.
Long COVID (LC) is defined as a complex of signs and symptoms developed during or after …