Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Aptamers are chemical antibodies possessing the capability of overcoming the limitations
posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …

Fluorescent compounds that can preferentially interact with certain nucleic acids are of great
importance in new drug discovery in a multitude of functions including fluorescence-based …

In the search for novel, effective inhibitors of High‐Mobility Group Box1 (HMGB1)—a protein
involved in various inflammatory and autoimmune diseases as well as in cancer—we herein …

The limitations associated with the in vivo use of the thrombin binding aptamer (TBA or TBA
15) have dramatically stimulated the search of suitable chemically modified analogues in …

Thrombin-binding aptamer (TBA), which forms a G-quadruplex (G4) structure with anti-
parallel topology, interacts with thrombin to inhibit its enzymatic activity. Here we show that …

Cancer is one of the diseases that causes a high mortality as it involves unregulated and
abnormal cell growth proliferation that can manifest in any body region. One of the typical …