Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …
Prevention of Congenital Cytomegalovirus Infection: Review and Case Series of Valaciclovir versus Hyperimmune Globulin Therapy
G Nigro, M Muselli… - Viruses, 2023 - mdpi.com
Cytomegalovirus (CMV) is the most common cause of congenital infections in developed
countries because is capable of infecting the fetus after both primary and recurrent maternal …
countries because is capable of infecting the fetus after both primary and recurrent maternal …
A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection
The respiratory system, especially the lung, is the key site of pathological injury induced by
SARS-CoV-2 infection. Given the low feasibility of targeted delivery of antibodies into the …
SARS-CoV-2 infection. Given the low feasibility of targeted delivery of antibodies into the …
Can the SARS-CoV-2 omicron variant confer natural immunity against COVID-19?
The coronavirus disease 2019 (COVID-19) pandemic is still ongoing, with no signs of
abatement in sight. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
abatement in sight. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Efficacy of COVID-HIGIV in animal models of SARS-CoV-2 infection
A Jha, D Barker, J Lew, V Manoharan, J van Kessel… - Scientific reports, 2022 - nature.com
In late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus
emerged in China and quickly spread into a worldwide pandemic. It has caused millions of …
emerged in China and quickly spread into a worldwide pandemic. It has caused millions of …
Transchromosomic bovines‐derived broadly neutralizing antibodies as potent biotherapeutics to counter important emerging viral pathogens with a special focus on …
ARA Saied, MSL Nascimento… - Journal of medical …, 2022 - Wiley Online Library
Historically, passive immunotherapy is an approved approach for protecting and treating
humans against various diseases when other alternative therapeutic options are …
humans against various diseases when other alternative therapeutic options are …
Neonatal sepsis and transient immunodeficiency: Potential for novel immunoglobulin therapies?
CR Beudeker, DC Vijlbrief, JM van Montfrans… - Frontiers in …, 2022 - frontiersin.org
Neonates, especially preterm neonates, have the highest risk of sepsis of all age groups.
Transient immaturity of the neonatal immune system is an important risk factor. Neonates …
Transient immaturity of the neonatal immune system is an important risk factor. Neonates …
SIR+ models: accounting for interaction-dependent disease susceptibility in the planning of public health interventions
Avoiding physical contact is regarded as one of the safest and most advisable strategies to
follow to reduce pathogen spread. The flip side of this approach is that a lack of social …
follow to reduce pathogen spread. The flip side of this approach is that a lack of social …
Passive Transfer of Animal-Derived Polyclonal Hyperimmune Antibodies Provides Protection of Mice from Lethal Lassa Virus Infection
L Oestereich, H Müller-Kräuter, E Pallasch, T Strecker - Viruses, 2023 - mdpi.com
Background: Lassa virus (LASV) can cause severe acute systemic infection in humans. No
approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics …
approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics …
Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase
KE Ramos, NMA Okba, J Tan, P Bandawane… - mBio, 2024 - Am Soc Microbiol
Monoclonal antibodies (mAbs) are an attractive therapeutic platform for the prevention and
treatment of influenza virus infection. There are two major glycoproteins on the influenza …
treatment of influenza virus infection. There are two major glycoproteins on the influenza …