The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Human brain function undergoes complex transformations across the lifespan. We
employed resting-state functional MRI and graph-theory approaches to systematically chart …

Cerebral white matter (WM) degeneration occurs with increasing age and is associated with
declining cognitive function. Research has shown that cardiorespiratory fitness and exercise …

Higher order speeded cognitive abilities depend on efficient coordination of activity across
the brain, rendering them vulnerable to age reductions in structural and functional brain …

Both normal ageing and neurodegenerative diseases cause morphological changes to the
brain. Age-related brain changes are subtle, nonlinear, and spatially and temporally …

Creating a healthy, social classroom environment. This book explains how the brain, as a
social organism, learns best throughout the lifespan, from our early schooling through late …

Executive function declines with age, but engaging in aerobic exercise may attenuate
decline. One mechanism by which aerobic exercise may preserve executive function is …

Magnetic resonance imaging volumetry studies report inverted U-patterns with increasing
white-matter (WM) volume into middle age suggesting protracted WM maturation compared …

Diffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25years,
diffusion MRI has been extraordinarily successful (with more than 300,000 entries on …

Cognitive decline is commonly observed in advanced aging even in the absence of disease.
Here we explore the possibility that normal aging is accompanied by disruptive alterations in …