In vitro performance of free and encapsulated bromelain

JA Ataide, LC Cefali, MC Figueiredo, LEO Braga… - Scientific reports, 2021 - nature.com
For centuries, bromelain has been used to treat a range of ailments, even though its
mechanism of action is not fully understood. Its therapeutic benefits include enzymatic …

Orally administered allyl sulfides from garlic ameliorate murine colitis

I Fasolino, AA Izzo, T Clavel, B Romano… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope Inflammatory bowel disease (IBD) is an incurable disease which affects millions of
people. Garlic (Allium sativum) preparations have been traditionally employed for the …

Encapsulation of bromelain in combined sodium alginate and amino acid carriers: Experimental design of simplex-centroid mixtures for digestibility evaluation

PC Ricardo, RL Serudo, Ş Ţălu, CV Lamarão… - Molecules, 2022 - mdpi.com
Bromelain has potential as an analgesic, an anti-inflammatory, and in cancer treatments.
Despite its therapeutic effects, this protein undergoes denaturation when administered …

[HTML][HTML] Depletion of mucin in mucin-producing human gastrointestinal carcinoma: results from in vitro and in vivo studies with bromelain and N-acetylcysteine

A Amini, S Masoumi-Moghaddam, A Ehteda, W Liauw… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Aberrant expression of membrane-associated and secreted mucins, as evident in epithelial
tumors, is known to facilitate tumor growth, progression and metastasis, and to provide …

Beneficial effects of anthocyanins from red cabbage (Brassica oleracea L. var. capitata L.) administration to prevent irinotecan-induced mucositis

T Tong, YH Niu, Y Yue, S Wu, H Ding - Journal of Functional Foods, 2017 - Elsevier
Intestinal mucositis is a common side effect of Irinotecan (CPT-11). Anthocyanins (ACs) from
red cabbage against CPT-11-induced mucositis were studied. Mice were given CPT-11 (75 …

Combined anthocyanins and bromelain supplement improves endothelial function and skeletal muscle oxygenation status in adults: A double-blind placebo …

EJ Pekas, J Shin, RJ Headid, WM Son… - British Journal of …, 2021 - cambridge.org
Anthocyanins and bromelain have gained significant attention due to their antioxidative and
anti-inflammatory properties. Both have been shown to improve endothelial function, blood …

Bromelain protects critically perfused musculocutaneous flap tissue from necrosis

A Weinzierl, Y Harder, D Schmauss, MD Menger… - Biomedicines, 2022 - mdpi.com
Bromelain has previously been shown to prevent ischemia-induced necrosis in different
types of tissues. In the present study, we, therefore, evaluated for the first time, the tissue …

Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms

U Kansakar, V Trimarco, MV Manzi, E Cervi, P Mone… - Nutrients, 2024 - mdpi.com
Bromelain is a mixture of proteolytic enzymes primarily extracted from the fruit and stem of
the pineapple plant (Ananas comosus). It has a long history of traditional medicinal use in …

Radical scavenging and anti‐proliferative capacity of three freeze‐dried tropical fruits

FJ Olivas‐Aguirre, GA González‐Aguilar… - … Journal of Food …, 2017 - Wiley Online Library
Tropical fruits are rich in antioxidant and anticancer phytochemicals, but their nutraceutical
potential could be enhanced by drying technologies. Mango cv. Ataulfo, papaya cv. Maradol …

Trends and prospects of plant proteases in therapeutics

AV Balakireva, NV Kuznetsova… - Current medicinal …, 2019 - ingentaconnect.com
The main function of proteases in any living organism is the cleavage of proteins resulting in
the degradation of damaged, misfolded and potentially harmful proteins and therefore …