Major depressive disorder (MDD) is a devastating mental disorder that affects up to 17% of
the population worldwide. Although brain-wide network-level abnormalities in MDD patients …

Mitochondria are the prime source of cellular energy, and are also responsible for important
processes such as oxidative stress, apoptosis and Ca2+ homeostasis. Depression is a …

Backgrounds Emerging studies reported that gut microbiota and fecal metabolites take part
in major depressive disorder (MDD) pathogenesis. However, the conclusions based on a …

Suicide is one of the leading causes of death worldwide. According to the World Health
Organization (WHO), every year, more than 700 thousand people die from this cause …

The microbiota-gut-brain axis is a bidirectional regulatory pathway between the brain and
the gastrointestinal tract, which plays an important role in maintain homeostasis. Gut …

Despite increasing prevalence and huge personal and societal burden, psychiatric diseases
still lack treatments which can control symptoms for a large fraction of patients. Increasing …

Premenstrual dysphoric disorder (PMDD) is characterized by the predictable onset of mood
and physical symptoms secondary to gonadal steroid fluctuation during the luteal phase of …

Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

Background Microglia-mediated neuroinflammation contributes to major depressive disorder
(MDD). Targeting microglia is a promising strategy for treating MDD. Patchouli alcohol (PA) …

Depression is considered the most important disorder affecting mental health. The aim of
this systematic integrative review was:(i) to describe the effects of supplementation with …