Research progress on dipeptidyl peptidase family: Structure, function and xenobiotic metabolism

XK Qian, J Zhang, XD Li, PF Song… - Current medicinal …, 2022 - ingentaconnect.com
Prolyl-specific peptidases or proteases, including Dipeptidyl Peptidase 2, 4, 6, 8, 9, 10,
Fibroblast Activation Protein, prolyl endopeptidase, and prolyl carboxypeptidase, belong to …

In vivo and in vitro comparison of the DPP-IV Inhibitory potential of food proteins from different origins after gastrointestinal digestion

L Fleury, B Deracinois, C Dugardin… - International Journal of …, 2022 - mdpi.com
Dipeptidyl-peptidase IV (DPP-IV) plays an essential role in glucose metabolism by
inactivating incretins. In this context, food-protein-derived DPP-IV inhibitors are promising …

Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile

C Agoni, I Stavropoulos, A Kirwan, MM Mysior, T Holton… - Molecules, 2023 - mdpi.com
Milk-derived peptides are known to confer anti-inflammatory effects. We hypothesised that
milk-derived cell-penetrating peptides might modulate inflammation in useful ways. Using …

Visualizing Dipeptidyl Peptidase-IV with an Advanced Non-π-Conjugated Fluorescent Probe for Early Thyroid Disease Diagnosis

J Li, M Ma, J Li, L Xu, D Song, P Ma, Q Fei - Analytical Chemistry, 2023 - ACS Publications
Early detection and effective treatment of thyroid cancer are vital due to the aggressiveness
and high mortality rate of the cancer. Nevertheless, the exploration of dipeptidyl peptidase-IV …

An optimized NIR fluorescent probe for visualizing DPP IV and applications in the diagnosis and therapy of inflammatory bowel diseases

S He, C Han, C Wang, X Huo, L Feng, Y Wang… - Sensors and Actuators B …, 2023 - Elsevier
Abstract Dipeptidyl peptidase IV (DPP IV), is a membrane glycoprotein with exopeptidase
activity, that mediates the degradation of glucagon-like-1 (GLP-1) and plays a vital role in …

Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1

J Zhang, QS Pan, XK Qian, XL Zhou… - Journal of Enzyme …, 2022 - Taylor & Francis
Pancreatic lipase (PL) is a well-known key target for the prevention and treatment of obesity.
Human carboxylesterase 1A (hCES1A) has become an important target for the treatment of …

Discovery of anthraquinones as DPP-IV inhibitors: Structure-activity relationships and inhibitory mechanism

HH Ma, J Zhang, CQ Li, LW Zou - Fitoterapia, 2023 - Elsevier
Abstract Dipeptidyl peptidase IV (DPP-IV) is an integrated type II transmembrane protein that
reduces endogenous insulin contents and increases plasma glucose levels by hydrolyzing …