Role of neuroglobin in the neuroprotective actions of estradiol and estrogenic compounds
Estradiol exerts neuroprotective actions that are mediated by the regulation of a variety of
signaling pathways and homeostatic molecules. Among these is neuroglobin, which is …
signaling pathways and homeostatic molecules. Among these is neuroglobin, which is …
Molecular Interactions between Neuroglobin and Cytochrome c: Possible Mechanisms of Antiapoptotic Defense in Neuronal Cells
MA Semenova, RV Chertkova, MP Kirpichnikov… - Biomolecules, 2023 - mdpi.com
Neuroglobin, which is a heme protein from the globin family that is predominantly expressed
in nervous tissue, can promote a neuronal survivor. However, the molecular mechanisms …
in nervous tissue, can promote a neuronal survivor. However, the molecular mechanisms …
Repurposing of tibolone in Alzheimer's disease
GE Barreto - Biomolecules, 2023 - mdpi.com
Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterised by the
accumulation of amyloid-beta and tau in the brain, leading to the progressive loss of memory …
accumulation of amyloid-beta and tau in the brain, leading to the progressive loss of memory …
Mitochondria dysfunction and inflammation in traumatic brain injury: androgens to the battlefront
AJ McGovern, GE Barreto - Androgens: Clinical Research and …, 2021 - liebertpub.com
The therapeutic response to traumatic brain injury (TBI) still lacks a strategy to treat its acute
and chronic phases. Given that TBI affects the lives of 1.5 million people a year, and the …
and chronic phases. Given that TBI affects the lives of 1.5 million people a year, and the …
Proteomic and bioinformatic investigation of altered pathways in neuroglobin-deficient breast cancer cells
Neuroglobin (NGB) is a myoglobin-like monomeric globin that is involved in several
processes, displaying a pivotal redox-dependent protective role in neuronal and extra …
processes, displaying a pivotal redox-dependent protective role in neuronal and extra …
Neuroglobin and mitochondria: The impact on neurodegenerative diseases
M Fiocchetti, P Cracco, E Montalesi… - Archives of Biochemistry …, 2021 - Elsevier
Dysfunctional mitochondria have severe consequences on cell functions including Reactive
Oxygen Specie (ROS) generation, alteration of mitochondrial signaling, Ca 2+ buffering, and …
Oxygen Specie (ROS) generation, alteration of mitochondrial signaling, Ca 2+ buffering, and …
New strategies for stroke therapy: nanoencapsulated neuroglobin
Stroke is a global health and socio-economic problem. However, no efficient preventive
and/or palliative treatments have yet been found. Neuroglobin (Ngb) is an endogen …
and/or palliative treatments have yet been found. Neuroglobin (Ngb) is an endogen …
Structural and (pseudo-) enzymatic properties of neuroglobin: Its possible role in neuroprotection
Neuroglobin (Ngb), the third member of the globin family, was discovered in human and
murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and …
murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and …
Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer's disease
E Poursaei, M Abolghasemi, S Bornehdeli… - Psychiatric …, 2022 - journals.lww.com
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Previous evidence …
MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Previous evidence …
[HTML][HTML] Identification of HMGCR, PPGARG and prohibitin as potential druggable targets of dihydrotestosterone for treatment against traumatic brain injury using …
AJ McGovern, J Gonzalez, D Ramírez… - International …, 2022 - Elsevier
Abstract Background Traumatic Brain Injury (TBI) has long-term devastating effects for which
there is no accurate and effective treatment for inflammation and chronic oxidative stress. As …
there is no accurate and effective treatment for inflammation and chronic oxidative stress. As …