Circulating tumor DNA: an emerging tool in gastrointestinal cancers

OB Alese, N Cook, A Ortega-Franco… - American Society of …, 2022 - ascopubs.org
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …

Follow-up of colorectal cancer and patterns of recurrence

PD Haria, AD Baheti, D Palsetia, SK Ankathi… - Clinical Radiology, 2021 - Elsevier
Colorectal cancer is one of the commonest cancers detected as also amongst the most
common causes of cancer death. Survival has improved due to better disease …

LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy

F Liu, Z Dai, Q Cheng, L Xu, L Huang, Z Liu, X Li… - Biomaterials, 2022 - Elsevier
Colorectal cancer (CRC) recurrence after surgical resection results in poor clinical
outcomes. Long noncoding RNAs (lncRNAs) are emerging new targets for mediating …

Phase II study of durvalumab monotherapy in patients with previously treated microsatellite instability‐high/mismatch repair‐deficient or POLE‐mutated metastatic or …

CR Oh, JE Kim, YS Hong, SY Kim… - … journal of cancer, 2022 - Wiley Online Library
The aim of our study is to evaluate the clinical efficacy of durvalumab in patients with
microsatellite instability‐high/mismatch repair‐deficient (MSI‐H/dMMR) or polymerase …

Racial and ethnic bias in risk prediction models for colorectal cancer recurrence when race and ethnicity are omitted as predictors

S Khor, EC Haupt, EE Hahn, LJL Lyons… - JAMA Network …, 2023 - jamanetwork.com
Importance Including race and ethnicity as a predictor in clinical risk prediction algorithms
has received increased scrutiny, but there continues to be a lack of empirical studies …

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the surveillance and survivorship care of patients after curative treatment of colon …

KM Hardiman, SI Felder, G Friedman… - Diseases of the Colon …, 2021 - journals.lww.com
More than 140,000 people in the United States are diagnosed annually with colorectal
cancer (CRC), and 5% to 40% of patients treated with curative intent develop a recurrence …

Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC)

BL Musher, JE Melson, G Amato, D Chan, M Hill… - … Biomarkers & Prevention, 2020 - AACR
Background: Most recurrences of early-stage colorectal cancer detected with current
surveillance measures are widespread and incurable. Circulating tumor DNA (ctDNA) may …

Racial disparities in recurrence and overall survival in patients with locoregional colorectal cancer

RA Snyder, CY Hu, SN Zafar… - JNCI: Journal of the …, 2021 - academic.oup.com
Background The purpose of this study was to determine the association between race and
long-term cancer outcomes (recurrence and overall survival) within a population of US …

[HTML][HTML] The effect of metformin on the survival of colorectal cancer patients with type 2 diabetes mellitus

Z Tarhini, K Manceur, J Magne, M Mathonnet, J Jost… - Scientific Reports, 2022 - nature.com
Evidence from previous studies suggests a protective effect of metformin in patients with
colorectal cancer (CRC). The aim of this study was to examine the associations between …

Proanthocyanidins inhibited colorectal cancer stem cell characteristics through Wnt/β‐catenin signaling

Y Chen, Z Yang, X He, W Zhu, Y Wang… - Environmental …, 2023 - Wiley Online Library
Abstract Background Cancer stem cells (CSCs) play a key role in tumor cell growth, drug
resistance, recurrence, and metastasis. Proanthocyanidins (PC) is widely existed in plants …