The highly diverse antiphage defence systems of bacteria
H Georjon, A Bernheim - Nature Reviews Microbiology, 2023 - nature.com
Bacteria and their viruses have coevolved for billions of years. This ancient and still ongoing
arms race has led bacteria to develop a vast antiphage arsenal. The development of high …
arms race has led bacteria to develop a vast antiphage arsenal. The development of high …
Bacterial defences: mechanisms, evolution and antimicrobial resistance
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …
microorganisms, including competing bacteria, bacteriophages and predators. In response …
[HTML][HTML] A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome
CN Vassallo, CR Doering, ML Littlehale… - Nature …, 2022 - nature.com
The ancient, ongoing coevolutionary battle between bacteria and their viruses,
bacteriophages, has given rise to sophisticated immune systems including restriction …
bacteriophages, has given rise to sophisticated immune systems including restriction …
[PDF][PDF] Phages and their satellites encode hotspots of antiviral systems
Bacteria carry diverse genetic systems to defend against viral infection, some of which are
found within prophages where they inhibit competing viruses. Phage satellites pose …
found within prophages where they inhibit competing viruses. Phage satellites pose …
[HTML][HTML] Systematic and quantitative view of the antiviral arsenal of prokaryotes
Bacteria and archaea have developed multiple antiviral mechanisms, and genomic
evidence indicates that several of these antiviral systems co-occur in the same strain. Here …
evidence indicates that several of these antiviral systems co-occur in the same strain. Here …
The oral microbiome: diversity, biogeography and human health
The human oral microbiota is highly diverse and has a complex ecology, comprising
bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and …
bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and …
Phages overcome bacterial immunity via diverse anti-defence proteins
E Yirmiya, A Leavitt, A Lu, AE Ragucci, C Avraham… - Nature, 2024 - nature.com
It was recently shown that bacteria use, apart from CRISPR–Cas and restriction systems, a
considerable diversity of phage resistance systems,,–, but it is largely unknown how phages …
considerable diversity of phage resistance systems,,–, but it is largely unknown how phages …
[PDF][PDF] Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors
Bacteria encode sophisticated anti-phage systems that are diverse and versatile and display
high genetic mobility. How this variability and mobility occurs remains largely unknown …
high genetic mobility. How this variability and mobility occurs remains largely unknown …
The evolutionary success of regulated cell death in bacterial immunity
Highlights•Many antiphage systems trigger regulated death of the infected cell.•Regulated
cell death protects the nearby population from the spread of infection.•Over 70% of …
cell death protects the nearby population from the spread of infection.•Over 70% of …
[HTML][HTML] Microbial defenses against mobile genetic elements and viruses: Who defends whom from what?
Prokaryotes have numerous mobile genetic elements (MGEs) that mediate horizontal gene
transfer (HGT) between cells. These elements can be costly, even deadly, and cells use …
transfer (HGT) between cells. These elements can be costly, even deadly, and cells use …