Convergence of oxytocin and dopamine signaling in neuronal circuits: Insights into the neurobiology of social interactions across species

V Rappeneau, F Castillo-Díaz - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Social behaviours are essential for animal survival, and the hypothalamic neuropeptide
oxytocin (OXT) critically impacts bonding, parenting, and decision-making. Dopamine (DA) …

Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear

A Bludau, U Schwartz, DM Zeitler, M Royer… - Molecular …, 2023 - nature.com
Social interactions are critical for mammalian survival and evolution. Dysregulation of social
behavior often leads to psychopathologies such as social anxiety disorder, denoted by …

[HTML][HTML] Neurobiological mechanisms underlying oxytocin-mediated parental behavior in rodents

K Inada - Neuroscience Research, 2024 - Elsevier
Parental behavior is essential for mammalian offspring to survive. Because of this
significance, elucidating the neurobiological mechanisms that facilitate parental behavior …

A prefrontal-habenular circuitry regulates social fear behaviour

Y Tian, J Zheng, X Zhu, X Liu, H Li, J Wang, Q Yang… - Brain, 2024 - academic.oup.com
The medial prefrontal cortex (mPFC) has been implicated in the pathophysiology of social
impairments including social fear. However, the precise subcortical partners that mediate …

[HTML][HTML] Mating-induced release of oxytocin in the mouse lateral septum: Implications for social fear extinction

CP Grossmann, C Sommer, IB Fahliogullari… - …, 2024 - Elsevier
In mammals, some physiological conditions are associated with the high brain oxytocin
(OXT) system activity. These include lactation in females and mating in males and females …

Robust GRK2/3/6-dependent desensitization of oxytocin receptor in neurons

K George, HTM Hoang, T Tibbs, RY Nagaraja, G Li… - iScience, 2024 - cell.com
Oxytocin plays critical roles in the brain as a neuromodulator, regulating social and other
affective behavior. However, the regulatory mechanisms controlling oxytocin receptor …

Developmental trajectory of social reward motivation from early adolescence into adulthood in female and male Long‐Evans rats

SH Murray, RJ Logan, AC Sheehan… - Developmental …, 2024 - Wiley Online Library
Most studies of adolescent and adult behavior involved one age group of each, whereas the
dynamic changes in brain development suggest that there may be behavioral flux in …

[HTML][HTML] Monitoring oxytocin signaling in the brain: More than a love story

ID Neumann - Comprehensive Psychoneuroendocrinology, 2023 - Elsevier
More than any other neuropeptide, oxytocin (OXT) is attracting the attention of
neurobiologists, psychologists, psychiatrists, evolutionary biologists and even economists. It …

Deciphering autism heterogeneity: a molecular stratification approach in four mouse models

C Gora, A Dudas, O Vaugrente, L Drobecq… - arXiv preprint arXiv …, 2024 - arxiv.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized
by impairments in social interaction, communication, as well as restrained or stereotyped …

[HTML][HTML] Age-related decline in social interaction is associated with decreased c-Fos induction in select brain regions independent of oxytocin receptor expression …

JR Ravenel, AE Perkins, A Tomczik, A Defendini… - Aging Brain, 2024 - Elsevier
Social behavior decreases with aging, and we have previously found a substantial decline
in social investigative behavior of old female rats. In this study we examined the neural …