[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine

MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …

Curcumin delivery and co-delivery based on nanomaterials as an effective approach for cancer therapy

M Pourmadadi, P Abbasi, MM Eshaghi… - Journal of Drug Delivery …, 2022 - Elsevier
Throughout the world, cancer is one of the main causes of mortality, threatening the public
health in many countries. As a result, cancer therapy researchers are paying increasing …

Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysis

H Kou, L Huang, M Jin, Q He, R Zhang… - Frontiers in …, 2023 - frontiersin.org
Objective The aim of this study is to evaluate the effectiveness and safety of curcumin in
rheumatoid arthritis patients. Methods A computerized search from PubMed, Embase …

[HTML][HTML] Curcumin, inflammation, and neurological disorders: How are they linked?

P Garodia, M Hegde, AB Kunnumakkara… - Integrative Medicine …, 2023 - Elsevier
Background: Despite the extensive research in recent years, the current treatment modalities
for neurological disorders are suboptimal. Curcumin, a polyphenol majorly found in …

Natural compounds as promising adjuvant agents in the treatment of gliomas

F Persano, G Gigli, S Leporatti - International Journal of Molecular …, 2022 - mdpi.com
In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …

Emerging paradigms in inflammatory disease management: Exploring bioactive compounds and the gut microbiota

T Benameur, C Porro, ME Twfieg, N Benameur… - Brain Sciences, 2023 - mdpi.com
The human gut microbiota is a complex ecosystem of mutualistic microorganisms that play a
critical role in maintaining human health through their individual interactions and with the …

[HTML][HTML] Challenges and opportunities for improving the druggability of natural product: Why need drug delivery system?

P Tang, T Shen, H Wang, R Zhang, X Zhang… - Biomedicine & …, 2023 - Elsevier
Bioactive natural products (BNPs) are the marrow of medicinal plants, which are the
secondary metabolites of organisms and have been the most famous drug discovery …

Exosomes in brain diseases: Pathogenesis and therapeutic targets

Q Si, L Wu, D Pang, P Jiang - MedComm, 2023 - Wiley Online Library
Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

Curcumin and analogues against head and neck cancer: from drug delivery to molecular mechanisms

C Zhao, X Zhou, Z Cao, L Ye, Y Cao, J Pan - Phytomedicine, 2023 - Elsevier
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most life-
threatening diseases which also causes economic burden worldwide. To overcome the …

Dual mechanism of action of curcumin in experimental models of multiple sclerosis

I ELBini-Dhouib, M Manai, N Neili, S Marzouki… - International Journal of …, 2022 - mdpi.com
Background: Multiple sclerosis (MS) is characterized by a combination of inflammatory and
demyelination processes in the spinal cord and brain. Conventional drugs generally target …