In the last decades, the advancement of knowledge in analgesia and sedation for critically ill
pediatric patients has been conspicuous and relevant. Many recommendations have …

Background Management and monitoring of pain and sedation to reduce discomfort as well
as side effects, such as over-and under-sedation, withdrawal syndrome and delirium, is an …

Background: Extended reality (XR) technology such as virtual and augmented reality is
increasingly being utilised in paediatric medicine due to its role in medical education and …

Abstract Study Objective We aimed to evaluate the efficacy and safety of ketamine in
ensuring comfort and sparing conventional drugs when used as an adjuvant for analgesia …

Introduction This systematic review aimed to evaluate the quality of clinical practice
guidelines (CPGs) and recommendations for managing pain, sedation, delirium, and …

Introduction Analgesia and sedation are essential for the care of children in the pediatric
intensive care unit (PICU); however, when prolonged, they may be associated with …

Background and Significance Advances in pediatric intensive care have led to markedly
improved survival rates in critically ill children. Approximately 70% of those children survive …

Introduction. Adequate sedation and analgesia is essential in the management of patients
requiring mechanical ventilation (MV). The implementation of protocols and their monitoring …

The survival of preterm infants continues to improve, along with an increased in neonatal
intensive care unit (NICU) management of chronic infants who are medically complex infants …

Background Ketamine has been considered as an adjunct for children who do not reach
their predefined target sedation depth. However, there is limited evidence regarding the use …