Implementing vancomycin population pharmacokinetic models: an app for individualized antibiotic therapy in critically ill patients

M Mena, JC Garcia, RH Bustos - Antibiotics, 2023 - mdpi.com
In individualized therapy, the Bayesian approach integrated with population
pharmacokinetic models (PopPK) for predictions together with therapeutic drug monitoring …

Risk of acute kidney injury based on vancomycin target trough attainment strategy: area-under-the-curve-guided Bayesian software, nomogram, or trough-guided …

JM Knight, T Iso, KK Perez, JT Swan… - Annals of …, 2024 - journals.sagepub.com
Background: Guidelines support area-under-the-curve (AUC) monitoring for vancomycin
dosing which may lower overall doses and reduce acute kidney injury (AKI). Objective: The …

Is It Still Beneficial to Monitor the Trough Concentration of Vancomycin? A Quantitative Meta-Analysis of Nephrotoxicity and Efficacy

W Yang, K Zhang, Y Chen, Y Fan, J Zhang - Antibiotics, 2024 - mdpi.com
This study conducted a quantitative meta-analysis to investigate the association of
vancomycin indicators, particularly area under the curve over 24 h (AUC24) and trough …

[HTML][HTML] Comparison of adverse events with vancomycin diluted in normal saline vs dextrose 5%

RC Ross, BA Kelly, RM Smith, AJ Franck - Federal Practitioner, 2021 - ncbi.nlm.nih.gov
Background IV vancomycin is widely used for infections caused by Gram-positive bacteria;
however, nephrotoxicity is commonly associated with its use. Clinical trials have shown an …

[PDF][PDF] Vancomycin AUC optimisation using minimal plasma concentration monitoring

AM Shaw - 2021 - ourarchive.otago.ac.nz
Vancomycin AUC optimisation using minimal plasma concentration monitoring Page 1
Vancomycin AUC optimisation using minimal plasma concentration monitoring A thesis …

[HTML][HTML] Comparison of Adverse Events With Vancomycin Diluted in Normal Saline vs Dextrose 5%

AJ Franck - mdedge.com
Background: IV vancomycin is widely used for infections caused by Gram-positive bacteria;
however, nephrotoxicity is commonly associated with its use. Clinical trials have shown an …