Gap junctions, which mediate intercellular communication, are key players in digestive
homeostasis. They are also frequently involved in gastrointestinal and liver pathology. This …

Glands were the first type of tissues in which the permissive role of gap junctions in the cell-
to-cell transfer of membrane-impermeant molecules was shown. During the 40 years that …

The aim of the study was to investigate the mechanisms of Ca2+ oscillation generation upon
activation of connexin-43 and regulation of the lipolysis/lipogenesis balance in white …

Direct communication between hepatocytes, mediated by gap junctions, constitutes a major
regulatory platform in the control of liver homeostasis, ranging from hepatocellular …

Alpha-particle irradiation of cells damages not only the irradiated cells but also nontargeted
bystander cells. It has been proposed that the bystander effect is caused by oxidants and …

Background and aims Being goalkeepers of liver homeostasis, gap junctions are also
involved in hepatotoxicity. However, their role in this process is ambiguous, as gap junctions …

Connexins and pannexins are key players in the control of cellular communication and thus
in the maintenance of tissue homeostasis. Inherent to this function these proteins are …

Endothelial cells (ECs) play many roles in vascular biology, including control of blood
pressure, blood clotting, atherosclerosis, angiogenesis, and inflammation. Gap junctions …

Cell‐to‐cell interactions via gap junctional communication and connexon hemichannels are
involved in the pathogenesis of diabetes. Gap junctions are highly specialized …

Connexin proteins are abundantly present in the digestive system. They primarily form gap
junctions, which control the intercellular exchange of critical homeostasis regulators. By …