The mouse-adapted pathogen Chlamydia muridarum (CM) induces pathology in the mouse
genital tract but fails to do so in the gastrointestinal tract. CM is cleared from both the genital …

Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. A licensed vaccine is not yet available, but the first vaccines have …

Hepatic CD4 tissue-resident memory T cells (TRM) are required for robust protection against
Salmonella infection; however, the generation of this T cell population is poorly understood …

Chlamydia vaccine approaches aspire to induce Th1 cells for optimal protection, despite the
fact that there is no direct evidence demonstrating Th1-mediated Chlamydia clearance from …

Urogenital tract infections with Chlamydia trachomatis have frequently been detected among
patients diagnosed with sexually transmitted infections, and such infections lead to …

Priming of T cells by antigen presenting cells (APCs) is essential for T cell fate decisions,
enabling T cells to migrate to specific tissues to exert their effector functions. Previously …

The protein basic helix-loop-helix family member e40 (BHLHE40) is a transcription factor
recently emerged as a key regulator of host immunity to infections, autoimmune diseases …

ABSTRACT CD4 T cell-dependent IFNγ production and antibody are the two best known
effectors for protective immunity against Chlamydia female reproductive tract (FRT) infection …

Persistent Chlamydia trachomatis infection is a risk factor for tubal infertility, and the
pathology is largely due to the inflammatory response; however, the underlying molecular …

Chlamydia trachomatis infections endanger women's health, but translational gaps between
animal models and human disease states persist. I compared immune responses in mice …