A mosaic of cost–benefit control over cortico-striatal circuitry
Dopamine contributes to cognitive control through well-established effects in both the
striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …
striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …
Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
The brain and behavior are under energetic constraints, limited by mitochondrial energy
transformation capacity. However, the mitochondria-behavior relationship has not been …
transformation capacity. However, the mitochondria-behavior relationship has not been …
Apathy and Motivation: Biological Basis and Drug Treatment
Apathy is a disabling syndrome associated with poor functional outcomes that is common
across a broad range of neurological and psychiatric conditions. Currently, there are no …
across a broad range of neurological and psychiatric conditions. Currently, there are no …
Development and validation of the physical effort scale (PES)
Objectives Previous literature has primarily viewed physical effort as an aversive
experience. However, recent research suggests that effort can also be valued positively …
experience. However, recent research suggests that effort can also be valued positively …
The controllosphere: The neural origin of cognitive effort.
CB Holroyd - Psychological Review, 2024 - psycnet.apa.org
Why do some mental activities feel harder than others? The answer to this question is
surprisingly controversial. Current theories propose that cognitive effort affords a …
surprisingly controversial. Current theories propose that cognitive effort affords a …
[HTML][HTML] A randomized clinical trial to evaluate the effects of safinamide on apathetic non-demented patients with Parkinson's disease
J Kulisevsky, S Martínez-Horta, A Campolongo… - Frontiers in …, 2022 - frontiersin.org
Background Apathy is highly prevalent and disabling in Parkinson's disease (PD).
Pharmacological options for its management lack sufficient evidence. Objective We studied …
Pharmacological options for its management lack sufficient evidence. Objective We studied …
The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease
J Wang, G Liu, K Xu, K Ai, W Huang… - Human Brain …, 2023 - Wiley Online Library
A growing body of evidence from neuroimaging studies suggests that inflammatory bowel
disease (IBD) is associated with functional and structural alterations in the central nervous …
disease (IBD) is associated with functional and structural alterations in the central nervous …
Theory and computation of nuclear shielding
T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …
Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response
T Santos-Silva, D Hazar Ülgen, CFB Lopes… - Translational …, 2023 - nature.com
Adolescent individuals exhibit great variability in cortical dynamics and behavioral
outcomes. The developing adolescent brain is highly sensitive to social experiences and …
outcomes. The developing adolescent brain is highly sensitive to social experiences and …
Multinuclear magnetic resonance spectroscopy at ultra-high-field: assessing human cerebral metabolism in healthy and diseased states
P Veeraiah, JFA Jansen - Metabolites, 2023 - mdpi.com
The brain is a highly energetic organ. Although the brain can consume metabolic substrates,
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …