A mosaic of cost–benefit control over cortico-striatal circuitry

A Westbrook, MJ Frank, R Cools - Trends in Cognitive Sciences, 2021 - cell.com
Dopamine contributes to cognitive control through well-established effects in both the
striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …

Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice

AM Rosenberg, M Saggar, AS Monzel, J Devine… - Nature …, 2023 - nature.com
The brain and behavior are under energetic constraints, limited by mitochondrial energy
transformation capacity. However, the mitochondria-behavior relationship has not been …

Apathy and Motivation: Biological Basis and Drug Treatment

H Costello, M Husain, JP Roiser - Annual Review of …, 2024 - annualreviews.org
Apathy is a disabling syndrome associated with poor functional outcomes that is common
across a broad range of neurological and psychiatric conditions. Currently, there are no …

Development and validation of the physical effort scale (PES)

B Cheval, S Maltagliati, DS Courvoisier… - Psychology of sport and …, 2024 - Elsevier
Objectives Previous literature has primarily viewed physical effort as an aversive
experience. However, recent research suggests that effort can also be valued positively …

The controllosphere: The neural origin of cognitive effort.

CB Holroyd - Psychological Review, 2024 - psycnet.apa.org
Why do some mental activities feel harder than others? The answer to this question is
surprisingly controversial. Current theories propose that cognitive effort affords a …

[HTML][HTML] A randomized clinical trial to evaluate the effects of safinamide on apathetic non-demented patients with Parkinson's disease

J Kulisevsky, S Martínez-Horta, A Campolongo… - Frontiers in …, 2022 - frontiersin.org
Background Apathy is highly prevalent and disabling in Parkinson's disease (PD).
Pharmacological options for its management lack sufficient evidence. Objective We studied …

The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease

J Wang, G Liu, K Xu, K Ai, W Huang… - Human Brain …, 2023 - Wiley Online Library
A growing body of evidence from neuroimaging studies suggests that inflammatory bowel
disease (IBD) is associated with functional and structural alterations in the central nervous …

Theory and computation of nuclear shielding

T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

T Santos-Silva, D Hazar Ülgen, CFB Lopes… - Translational …, 2023 - nature.com
Adolescent individuals exhibit great variability in cortical dynamics and behavioral
outcomes. The developing adolescent brain is highly sensitive to social experiences and …

Multinuclear magnetic resonance spectroscopy at ultra-high-field: assessing human cerebral metabolism in healthy and diseased states

P Veeraiah, JFA Jansen - Metabolites, 2023 - mdpi.com
The brain is a highly energetic organ. Although the brain can consume metabolic substrates,
such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult …