[HTML][HTML] Evolving concepts on inflammatory biomarkers and malnutrition in chronic kidney disease

F Graterol Torres, M Molina, J Soler-Majoral… - Nutrients, 2022 - mdpi.com
While patient care, kidney replacement therapy, and transplantation techniques for chronic
kidney disease (CKD) have continued to progress, the incidence of malnutrition disorders in …

[HTML][HTML] Short-chain fatty acids in chronic kidney disease: Focus on inflammation and oxidative stress regulation

G Magliocca, P Mone, BR Di Iorio, A Heidland… - International Journal of …, 2022 - mdpi.com
Chronic Kidney Disease (CKD) is a debilitating disease associated with several secondary
complications that increase comorbidity and mortality. In patients with CKD, there is a …

[HTML][HTML] Biotics (Pre-, pro-, post-) and uremic toxicity: implications, mechanisms, and possible therapies

L Mitrea, M Medeleanu, CR Pop, AM Rotar, DC Vodnar - Toxins, 2023 - mdpi.com
In recent years, more scientific data have pointed out the close connection between
intestinal microbial community, nutritional habits, lifestyle, and the appearance of various …

[HTML][HTML] The gut–organ axis within the human body: gut dysbiosis and the role of prebiotics

G Saxami, EN Kerezoudi, C Eliopoulos, D Arapoglou… - Life, 2023 - mdpi.com
The human gut microbiota (GM) is a complex microbial ecosystem that colonises the
gastrointestinal tract (GIT) and is comprised of bacteria, viruses, fungi, and protozoa. The GM …

[HTML][HTML] Hypomagnesemia as a risk factor and accelerator for vascular aging in diabetes mellitus and chronic kidney disease

ÁG Pethő, M Tapolyai, M Browne, T Fülöp - Metabolites, 2023 - mdpi.com
The age-old axiom that one is as old as his or her vessels are, calls for ongoing critical re-
examination of modifiable risk factors of accelerated vascular ageing in chronic kidney …

[HTML][HTML] 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) induces cell death through ferroptosis and acts as a trigger of apoptosis in kidney cells

JS Park, DH Kim, HI Choi, CS Kim, EH Bae… - Cell Death & …, 2023 - nature.com
Ferroptosis is a cell death mechanism characterized by intracellular iron accumulation and
lipid peroxidation. Effects of uremic toxins on ferroptosis in the kidney are not well …

[HTML][HTML] Changes in cardiac function during the development of uremic cardiomyopathy and the effect of salvianolic acid B administration in a rat model

D Ma, AS Mandour, A Elfadadny… - Frontiers in veterinary …, 2022 - frontiersin.org
Background Uremic cardiomyopathy (UC), the main cause of death in progressive chronic
kidney disease (CKD), is characterized by diastolic dysfunction. Intraventricular pressure …

Effects of resveratrol on inflammation and oxidative stress induced by the uremic toxin indoxyl sulfate in Murine macrophage-like RAW 264.7

L Alvarenga, JF Saldanha, MB Stockler-Pinto… - Biochimie, 2023 - Elsevier
Indoxyl sulfate (IS) is a uremic toxin produced by the gut microbiota that commonly
accumulates in patients with chronic kidney disease (CKD) and can be harmful. Resveratrol …

[HTML][HTML] Zebrafish as a model of cardiac pathology and toxicity: spotlight on uremic toxins

A Coppola, P Lombari, E Mazzella… - International Journal of …, 2023 - mdpi.com
Chronic kidney disease (CKD) is an increasing health care problem. About 10% of the
general population is affected by CKD, representing the sixth cause of death in the world …

Study of the association between serum levels of kynurenine and cardiovascular outcomes and overall mortality in chronic kidney disease

C El Chamieh, IA Larabi… - Clinical kidney …, 2024 - academic.oup.com
Background Kynurenine is a protein-bound uremic toxin. Its circulating levels are increased
in chronic kidney disease (CKD). Experimental studies showed that it exerted deleterious …