[HTML][HTML] Cytokine storm

DC Fajgenbaum, CH June - New England Journal of Medicine, 2020 - Mass Medical Soc
Cytokine Storm Cytokine storm, a life-threatening disorder involving cytokine elevations and
immune-cell hyperactivation, has various causes and is characterized by constitutional …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …

[HTML][HTML] Kawasaki disease: pathophysiology and insights from mouse models

M Noval Rivas, M Arditi - Nature Reviews Rheumatology, 2020 - nature.com
Kawasaki disease is an acute febrile illness and systemic vasculitis of unknown aetiology
that predominantly afflicts young children, causes coronary artery aneurysms and can result …

[HTML][HTML] Kawasaki disease: pathophysiology and insights from mouse models

MN Rivas, M Arditi - Nature reviews. Rheumatology, 2020 - ncbi.nlm.nih.gov
Kawasaki disease is an acute febrile illness and systemic vasculitis of unknown aetiology
that predominantly afflicts young children, causes coronary artery aneurysms and can result …

[HTML][HTML] Sexual dimorphism in bacterial infections

ER Vázquez-Martínez, E García-Gómez… - Biology of sex …, 2018 - Springer
Background Sex differences are important epidemiological factors that impact in the
frequency and severity of infectious diseases. A clear sexual dimorphism in bacterial …

The immunology of sepsis

S Sriskandan, DM Altmann - … Journal of Pathology: A Journal of …, 2008 - Wiley Online Library
Sepsis, the systemic inflammatory response to infection, is considered the major cause of
death among critically ill patients in the developed world. While there is a general view that …

[HTML][HTML] Staphylococcal superantigens: pyrogenic toxins induce toxic shock

T Krakauer - Toxins, 2019 - mdpi.com
Staphylococcal enterotoxin B (SEB) and related superantigenic toxins produced by
Staphylococcus aureus are potent activators of the immune system. These protein toxins …

Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections

Y Wang, S Liu, L Li, L Li, X Zhou, M Wan, P Lou… - Journal of Controlled …, 2022 - Elsevier
Cytokine storms are a primary cause of multiple organ damage and death after severe
infections, such as SARS-CoV-2. However, current single cytokine-targeted strategies …

[HTML][HTML] Manipulation of innate and adaptive immunity by staphylococcal superantigens

SW Tuffs, SMM Haeryfar, JK McCormick - Pathogens, 2018 - mdpi.com
Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …

Hypervirulence of a Rough Variant of the Mycobacterium abscessus Type Strain

E Catherinot, J Clarissou, G Etienne, F Ripoll… - Infection and …, 2007 - Am Soc Microbiol
We isolated a rough variant of Mycobacterium abscessus CIP 104536T during experimental
infection of mice. We show that this variant has lost the ability to produce glycopeptidolipids …