Recent advances in enzyme-activated NIR fluorescent probes for biological applications

H Jeong, X Wu, JS Lee, J Yoon - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …

Recent progress of fluorescent probes for the detection of alkaline phosphatase (ALP): A review

H Zhang, Q Ju, S Pang, N Wei, Y Zhang - Dyes and Pigments, 2021 - Elsevier
Alkaline phosphatase (ALP) that is a crucial biomarker for the diagnosis of hepatobiliary and
skeletal diseases is widely distributed in human bone, liver, intestine, placenta and other …

Near-infrared fluorescent probe with large stokes shift for imaging of hydrogen sulfide in tumor-bearing mice

L Yan, QS Gu, WL Jiang, M Tan, ZK Tan… - Analytical …, 2022 - ACS Publications
Hydrogen sulfide (H2S) is an important endogenous gas signal molecule in living system,
which participates in a variety of physiological processes. Very recent evidence has …

Monitoring the fluctuation of hydrogen peroxide in diabetes and its complications with a novel near-infrared fluorescent probe

WX Wang, WL Jiang, GJ Mao, M Tan, J Fei… - Analytical …, 2021 - ACS Publications
Diabetes is one of the metabolic diseases marked by hyperglycemia and is often
accompanied by the occurrence of some complications. As a biomarker of oxidative stress …

Dihydroxanthene-based near-infrared fluorescent probes for monitoring mitochondrial viscosity in living cells and mice

X Wu, G Fu, Y Li, S Li, Q Zhao, F Kong, L Li… - Analytical …, 2023 - ACS Publications
Aberrant mitochondrial viscosity is closely associated with many diseases and cellular
malfunctions. Thus, the development of reliable methods for monitoring mitochondrial …

Targeted Enrichment of Enzyme‐Instructed Assemblies in Cancer Cell Lysosomes Turns Immunologically Cold Tumors Hot

S Ji, J Li, X Duan, J Zhang, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Lysosome‐relevant cell death induced by lysosomal membrane permeabilization (LMP) has
recently attracted increasing attention. However, nearly no studies show that currently …

A novel benzothiazolin-based fluorescent probe for hypobromous acid and its application in environment and biosystems

X Zhang, C Liu, H Zhu, K Wang, M Liu, X Li, L Ma, M Yu… - Talanta, 2024 - Elsevier
Studies have shown that hypobromous acid (HOBr) produced during chlorination
disinfection of tap water can react with some organic matter in water to form toxic brominated …

An activatable probe with aggregation‐induced emission for detecting and imaging herbal medicine induced liver injury with optoacoustic imaging and NIR‐II …

L Sun, J Ouyang, Y Ma, Z Zeng, C Zeng… - Advanced …, 2021 - Wiley Online Library
Whilte herbal medicines are widely used for health promotion and therapy for chronic
conditions, inappropriate use of them may cause adverse effects like liver injury, and …

Ratiometric detection and bioimaging of endogenous alkaline phosphatase by a NIR fluorescence probe

YA Feng, H Xu, Y Zhou, BJ Wang, J Xiao… - Sensors and Actuators B …, 2022 - Elsevier
A novel near-infrared (NIR) fluorescent probe (SWJT-3) was designed based on phosphate
protection of the electron donating group of the hemicyanine for the ratiometric …

Design of a near-infrared fluoro-photoacoustic probe for rapid imaging of carboxylesterase in liver injury

H Chen, K Li, L Yuan, XB Zhang - Chemical Communications, 2023 - pubs.rsc.org
Carboxylesterase (CE) is crucial in metabolizing ester-containing biomolecules and is
particularly significant in liver metabolic diseases. Herein, we present the first activatable …