Endophytic fungi: from symbiosis to secondary metabolite communications or vice versa?

B Alam, J Lǐ, Q Gě, MA Khan, J Gōng… - Frontiers in Plant …, 2021 - frontiersin.org
Endophytic fungi (EF) are a group of fascinating host-associated fungal communities that
colonize the intercellular or intracellular spaces of host tissues, providing beneficial effects to …

Endophytic fungi: hidden treasure chest of antimicrobial metabolites interrelationship of endophytes and metabolites

P Jha, T Kaur, I Chhabra, A Panja, S Paul… - Frontiers in …, 2023 - frontiersin.org
Endophytic fungi comprise host-associated fungal communities which thrive within the
tissues of host plants and produce a diverse range of secondary metabolites with various …

Recent advances in triterpenoid pathway elucidation and engineering

S Dinday, S Ghosh - Biotechnology Advances, 2023 - Elsevier
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …

Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis

W Sun, Q Yin, H Wan, R Gao, C Xiong, C Xie… - Nature …, 2023 - nature.com
Horse chestnut (Aesculus chinensis) is an important medicinal tree that contains various
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …

A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis

V Forman, D Luo, F Geu-Flores, R Lemcke… - Nature …, 2022 - nature.com
The ginkgo tree (Ginkgo biloba) is considered a living fossil due to its 200 million year's
history under morphological stasis. Its resilience is partly attributed to its unique set of …

Cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters

CLM Gilchrist, TJ Booth, B van Wersch… - Bioinformatics …, 2021 - academic.oup.com
Motivation Genes involved in coordinated biological pathways, including metabolism, drug
resistance and virulence, are often collocalized as gene clusters. Identifying homologous …

The emerging role of biosynthetic gene clusters in plant defense and plant interactions

G Polturak, A Osbourn - PLoS pathogens, 2021 - journals.plos.org
The plant kingdom produces a diverse array of chemicals, collectively making an estimated
105 to 106 different metabolites [1, 2]. These compounds are either known or likely to have …

Plant metabolic gene clusters in the multi-omics era

C Zhan, S Shen, C Yang, Z Liu, AR Fernie… - Trends in Plant …, 2022 - cell.com
Secondary metabolism in plants gives rise to a vast array of small-molecule natural
products. The discovery of operon-like gene clusters in plants has provided a new …

Metabolomics and complementary techniques to investigate the plant phytochemical cosmos

H Tsugawa, A Rai, K Saito, R Nakabayashi - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …

Three chromosome-scale Papaver genomes reveal punctuated patchwork evolution of the morphinan and noscapine biosynthesis pathway

X Yang, S Gao, L Guo, B Wang, Y Jia, J Zhou… - Nature …, 2021 - nature.com
For millions of years, plants evolve plenty of structurally diverse secondary metabolites (SM)
to support their sessile lifestyles through continuous biochemical pathway innovation. While …