Some viruses are known to be associated with the onset of specific cancers. These
microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer …

Abstract Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase
family. Originally, it was identified as a membrane protein involved in maintaining plasma …

Human T-cell lymphotropic virus type 1 (HTLV-1) is the first identified human retrovirus
responsible for two significant diseases: HTLV-1-associated myelopathy/tropical spastic …

Introduction There are difficulties in creating direct antiviral drugs for all viruses, including
new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed …

Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …

Human T-Lymphotropic Virus type-1 (HTLV-1) is a unique retrovirus associated with both
leukemogenesis and a specific neuroinflammatory condition known as HTLV-1-Associated …

MCL-1 is the prosurvival member of the Bcl-2 family. It prevents the induction of
mitochondria-dependent apoptosis. The molecular mechanisms dictating the host cell …

ABSTRACT Interferon-gamma (IFN-γ) plays a crucial role in viral infections by preventing
viral replication and in the promotion of innate and adaptive immune responses. However …

Several studies suggest that HTLV-1 infection may be associated with a wider spectrum of
neurological and clinical manifestations that do not meet diagnostic criteria for HAM. These …

Background and Objectives: Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive
T-cell lymphoproliferative disease associated with the human T-cell lymphotropic virus type I …