Alzheimer's disease is a progressive neurodegenerative disease characterized by the
presence of amyloid-β plaques in the extracellular environment and aggregates of Tau …

In addition to the amyloidogenic pathway, amyloid precursor protein (APP) can be cleaved
by α-secretases, producing soluble and neuroprotective APP alpha (sAPPα) …

Chronic neurodegenerative diseases are now associated with obesity and diabetes and
linked to the developing and developed world. Interests in healthy diets have escalated that …

Alzheimer's disease (AD) is the main cause of dementia and a major health issue
worldwide. The complexity of the pathology continues to challenge its comprehension and …

Alzheimer's disease (AD) is the primary cause of dementia in the elderly and one of the
major health problems worldwide. Since its first description by Alois Alzheimer in 1907 …

Abstract Alzheimer's disease (AD), a late onset neurodegenerative disorder is characterized
by the loss of memory, disordered cognitive function, caused by accumulation of amyloid-β …

Arrestins are multifunctional proteins that regulate G-protein-coupled receptor (GPCR)
desensitization, signaling, and internalization. The arrestin family consists of four subtypes …

G-protein-coupled receptors (GPCRs) form the largest receptor family, relay environmental
stimuli to changes in cell behavior and represent prime drug targets. Many GPCRs are …

Background and Purpose Alzheimer's disease (AD) is a neurodegenerative disease
characterized by progressive cognitive decline, and women account for 60% of diagnosed …

The locus coeruleus-noradrenergic (LC-NA) system supplies the cerebral cortex with
norepinephrine, a key modulator of cognition. Neurodegeneration of the LC is an early …