Radiopharmaceutical therapy in cancer: clinical advances and challenges
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …
Radionuclides for targeted therapy: physical properties
C Stokke, M Kvassheim, J Blakkisrud - Molecules, 2022 - mdpi.com
A search in PubMed revealed that 72 radionuclides have been considered for molecular or
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …
EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor-and PSMA-targeting ligands
K Sjögreen Gleisner, N Chouin, PM Gabina… - European journal of …, 2022 - Springer
The purpose of the EANM Dosimetry Committee is to provide recommendations and
guidance to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals …
guidance to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals …
ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …
inception in 1925, has had as its principal objective the development of internationally …
Phase II trial demonstrates the efficacy and safety of individualized, dosimetry-based 177Lu-DOTATATE treatment of NET patients
A Sundlöv, KS Gleisner, J Tennvall… - European journal of …, 2022 - Springer
Abstract Purpose Radionuclide therapy with 177Lu-DOTATATE is well established for
patients with advanced somatostatin receptor–positive neuroendocrine tumors with a …
patients with advanced somatostatin receptor–positive neuroendocrine tumors with a …
EANM position paper on article 56 of the Council Directive 2013/59/Euratom (basic safety standards) for nuclear medicine therapy
M Konijnenberg, K Herrmann, C Kobe… - European journal of …, 2021 - Springer
Executive Summary The EC Directive 2013/59/Euratom states in article 56 that exposures of
target volumes in nuclear medicine treatments shall be individually planned and their …
target volumes in nuclear medicine treatments shall be individually planned and their …
OpenDose: open-access resource for nuclear medicine dosimetry
Radiopharmaceutical dosimetry depends on the localization in space and time of
radioactive sources and requires the estimation of the amount of energy emitted by the …
radioactive sources and requires the estimation of the amount of energy emitted by the …
Tumor response to radiopharmaceutical therapies: the knowns and the unknowns
Radiopharmaceutical therapy (RPT) is defined as the delivery of radioactive atoms to tumor-
associated targets. In RPT, imaging is built into the mode of treatment since the …
associated targets. In RPT, imaging is built into the mode of treatment since the …
Dosimetry methods and clinical applications in peptide receptor radionuclide therapy for neuroendocrine tumours: a literature review
DMV Huizing, BJ de Wit-van der Veen, M Verheij… - EJNMMI research, 2018 - Springer
Background The main challenge for systemic radiation therapy using radiopharmaceuticals
(SRT) is to optimise the dose delivered to the tumour, while minimising normal tissue …
(SRT) is to optimise the dose delivered to the tumour, while minimising normal tissue …
EANM position paper on the role of radiobiology in nuclear medicine
A Aerts, U Eberlein, S Holm, R Hustinx… - European journal of …, 2021 - Springer
With an increasing variety of radiopharmaceuticals for diagnostic or therapeutic nuclear
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …