Effects of nanoparticle size and shape in clathrin-mediated endocytosis
W Xu, X Liu, X Liu - Journal of Applied Physics, 2022 - pubs.aip.org
Nanoparticles have been extensively adopted to deliver therapeutic drug molecules to cells
through clathrin-mediated endocytosis (CME). The size and shape of nanoparticles are …
through clathrin-mediated endocytosis (CME). The size and shape of nanoparticles are …
Primary Human Breast Cancer‐Associated Endothelial Cells Favor Interactions with Nanomedicines
Cancer nanomedicines predominately rely on transport processes controlled by tumor‐
associated endothelial cells to deliver therapeutic and diagnostic payloads into solid tumors …
associated endothelial cells to deliver therapeutic and diagnostic payloads into solid tumors …
O-GlcNAc transferase modulates the cellular endocytosis machinery by controlling the formation of clathrin-coated pits
S Rahmani, H Ahmed, O Ibazebo… - Journal of Biological …, 2023 - ASBMB
Clathrin-mediated endocytosis (CME) controls the internalization and function of a wide
range of cell surface proteins. CME occurs by the assembly of clathrin and many other …
range of cell surface proteins. CME occurs by the assembly of clathrin and many other …
Spatiotemporal organization and correlation of tip-focused exocytosis and endocytosis in regulating pollen tube tip growth
Pollen tube polar growth is a key cellular process during plant fertilization and is regulated
by tip-focused exocytosis and endocytosis. However, the spatiotemporal dynamics and …
by tip-focused exocytosis and endocytosis. However, the spatiotemporal dynamics and …
ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals
N Pashkova, L Gakhar, L Yu, NJ Schnicker, AY Minard… - Elife, 2021 - elifesciences.org
Attachment of ubiquitin (Ub) to cell surface proteins serves as a signal for internalization via
clathrin-mediated endocytosis (CME). How ubiquitinated membrane proteins engage the …
clathrin-mediated endocytosis (CME). How ubiquitinated membrane proteins engage the …
Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis
PJ Cossar, D Cardoso, D Mathwin, CC Russell… - European Journal of …, 2023 - Elsevier
Abstract Wiskostatin (1-(3, 6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino) propan-2-ol)(1) is
a carbazole-based compound reported as a specific and relatively potent inhibitor of the N …
a carbazole-based compound reported as a specific and relatively potent inhibitor of the N …
Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis
Eukaryotic cells use clathrin-mediated endocytosis to take up a large range of extracellular
cargos. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains …
cargos. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains …
[HTML][HTML] Antagonistic regulation controls clathrin-mediated endocytosis: AP2 adaptor facilitation vs restraint from clathrin light chains
L Redlingshöfer, FM Brodsky - Cells & Development, 2021 - Elsevier
Orchestration of a complex network of protein interactions drives clathrin-mediated
endocytosis (CME). A central role for the AP2 adaptor complex beyond cargo recognition …
endocytosis (CME). A central role for the AP2 adaptor complex beyond cargo recognition …
Coarse-grained simulations suggest potential competing roles of phosphoinositides and amphipathic helix structures in membrane curvature sensing of the AP180 N …
A Belessiotis-Richards, AH Larsen… - The Journal of …, 2022 - ACS Publications
The generation and sensing of membrane curvature by proteins has become of increasing
interest to researchers with multiple mechanisms, from hydrophobic insertion to protein …
interest to researchers with multiple mechanisms, from hydrophobic insertion to protein …
Imaging nanoscale axial dynamics at the basal plasma membrane
TJ Nawara, AL Mattheyses - The international journal of biochemistry & cell …, 2023 - Elsevier
Understanding of how energetically unfavorable plasma membrane shapes form, especially
in the context of dynamic processes in living cells or tissues like clathrin-mediated …
in the context of dynamic processes in living cells or tissues like clathrin-mediated …