Background: The coronavirus disease 2019 (COVID-19) can have a variety of effects on
pregnant women, from mild symptoms to severe complications. Those with underlying …

Proteins that drive processes like clathrin-mediated endocytosis (CME) are expressed at
various copy numbers within a cell, from hundreds (eg auxilin) to millions (eg clathrin) …

Clathrin-mediated endocytosis (CME) is the main mechanism by which mammalian cells
control their cell surface proteome. Proper operation of the pivotal CME cargo-adaptor AP2 …

Highlights•Niche signals support leukemia development, while driving progression and
relapse.•Endocytosis controls cellular processes that are essential in leukemia.•Targeting …

Abstract AP-1 and AP-2 adaptor protein complexes mediate clathrin-dependent trafficking at
the trans-Golgi network (TGN) and the plasma membrane, respectively. Whereas AP-1 is …

Clathrin-mediated endocytosis (CME) controls the internalization and function of a wide
range of cell surface proteins. CME occurs by the assembly of clathrin and many other …

Clathrin-mediated endocytosis (CME) is an essential pathway for eukaryotic cells to
internalize materials, such as nutrients and signaling proteins (1). CME occurs via the …

Clathrin-mediated endocytosis (CME) is the main mechanism by which mammalian cells
control their cell surface proteome. Proper operation of the pivotal CME cargo-adaptor AP2 …

Clathrin-mediated endocytosis (CME) begins with the nucleation of clathrin assembly on the
plasma membrane, followed by stabilization and growth/maturation of clathrin-coated pits …

Cell biologist Sandra L. Schmid has compared some of her skills to that of a watchmaker.“I
like to take things apart, put them back together, and understand exactly how they work,” she …