Unmethylated cytosine–phosphate–guanine (CpG) oligodeoxynucleotides (ODNs), which
were therapeutic DNA with high immunostimulatory activity, have been applied in …

US7785610B2 - Chimeric immunomodulatory compounds and methods of using the same—III
- Google Patents US7785610B2 - Chimeric immunomodulatory compounds and methods of …

There has been significant interest in the potential of cytosine–guanine (CpG) containing
oligodeoxynucleotides (ODN) as an immunotherapy for malignant, infectious and allergic …

CD40/CD40 ligand interactions have a central role in the induction of both humoral and
cellular immunity. In this study, we examined whether a plasmid expressing CD40 …

Phosphorothioate oligodeoxynucleotides with CpG motifs (CpG-ODNs) activate various
immune cell subsets and induce production of numerous cytokines. To evaluate whether …

Tumor cells are typically poorly immunogenic. The same mechanisms that evolved to avoid
the induction of immune responses against self tissues, and, hence, autoimmune disease …

Oligodeoxynucleotides (ODN) which contain immunostimulatory CG motifs (CpG ODN) can
promote T helper 1 (Th1) responses, an adjuvant activity that is desirable for vaccination …

Biotechnological Production of Bioactive Compounds provides insights on the most recent
innovations, trends, concerns, solutions and practical challenges encountered in the fields of …

There is a current need for safe, cheap, and effective vaccine adjuvants, to combine with sub‐
unit antigens to enhance their immunogenicity. In this study we have used probiotic Bacillus …

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs act as immune
adjuvants, accelerating and boosting antigen-specific antibody responses by up to 500-fold …