[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses

Y Wang, J Fang, B Liu, C Shao, Y Shi - Cell stem cell, 2022 - cell.com
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Shattering barriers toward clinically meaningful MSC therapies

O Levy, R Kuai, EMJ Siren, D Bhere, Y Milton… - Science …, 2020 - science.org
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …

Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Cell therapies in the clinic

LLW Wang, ME Janes, N Kumbhojkar… - Bioengineering & …, 2021 - Wiley Online Library
Cell therapies have emerged as a promising therapeutic modality with the potential to treat
and even cure a diverse array of diseases. Cell therapies offer unique clinical and …

Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise

TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …

[HTML][HTML] Cell or cell membrane-based drug delivery systems

S Tan, T Wu, D Zhang, Z Zhang - Theranostics, 2015 - ncbi.nlm.nih.gov
Natural cells have been explored as drug carriers for a long period. They have received
growing interest as a promising drug delivery system (DDS) until recently along with the …

Skin cancer and new treatment perspectives: A review

MCF Simoes, JJS Sousa, AACC Pais - Cancer letters, 2015 - Elsevier
Skin cancers are by far the most common malignancy of humans, particularly in the white
population. The growing incidence of cutaneous malignancies has heralded the need for …

Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment

N Ghasemi Darestani, AI Gilmanova… - Cell Communication and …, 2023 - Springer
Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

RH Lee, AA Pulin, MJ Seo, DJ Kota, J Ylostalo… - Cell stem cell, 2009 - cell.com
Quantitative assays for human DNA and mRNA were used to examine the paradox that
intravenously (iv) infused human multipotent stromal cells (hMSCs) can enhance tissue …

Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

SR Baglio, DM Pegtel, N Baldini - Frontiers in physiology, 2012 - frontiersin.org
Mesenchymal stem cells (MSCs) are adult multipotent cells that give rise to various cell
types of the mesodermal germ layer. MSCs are of great interest in the field of regenerative …