Neural tissue engineering options for peripheral nerve regeneration

X Gu, F Ding, DF Williams - Biomaterials, 2014 - Elsevier
Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to
autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are …

Trends in the design of nerve guidance channels in peripheral nerve tissue engineering

V Chiono, C Tonda-Turo - Progress in neurobiology, 2015 - Elsevier
The current trend of peripheral nerve tissue engineering is the design of advanced nerve
guidance channels (NGCs) acting as physical guidance for regeneration of nerves across …

Three-dimensional printing of high-content graphene scaffolds for electronic and biomedical applications

AE Jakus, EB Secor, AL Rutz, SW Jordan… - ACS …, 2015 - ACS Publications
The exceptional properties of graphene enable applications in electronics, optoelectronics,
energy storage, and structural composites. Here we demonstrate a 3D printable graphene …

3D fabrication with integration molding of a graphene oxide/polycaprolactone nanoscaffold for neurite regeneration and angiogenesis

Y Qian, J Song, X Zhao, W Chen, Y Ouyang… - Advanced …, 2018 - Wiley Online Library
Treating peripheral nerve injury faces major challenges and may benefit from bioactive
scaffolds due to the limited autograft resources. Graphene oxide (GO) has emerged as a …

Approaches to peripheral nerve repair: generations of biomaterial conduits yielding to replacing autologous nerve grafts in craniomaxillofacial surgery

R Gaudin, C Knipfer, A Henningsen… - BioMed research …, 2016 - Wiley Online Library
Peripheral nerve injury is a common clinical entity, which may arise due to traumatic,
tumorous, or even iatrogenic injury in craniomaxillofacial surgery. Despite advances in …

Molecular mechanisms involved in Schwann cell plasticity

A Boerboom, V Dion, A Chariot… - Frontiers in molecular …, 2017 - frontiersin.org
Schwann cell incredible plasticity is a hallmark of the utmost importance following nerve
damage or in demyelinating neuropathies. After injury, Schwann cells undergo …

Strategic design and fabrication of nerve guidance conduits for peripheral nerve regeneration

MD Sarker, S Naghieh, AD McInnes… - Biotechnology …, 2018 - Wiley Online Library
Nerve guidance conduits (NGCs) have been drawing considerable attention as an aid to
promote regeneration of injured axons across damaged peripheral nerves. Ideally, NGCs …

3D in vitro modeling of the central nervous system

AM Hopkins, E DeSimone, K Chwalek… - Progress in …, 2015 - Elsevier
There are currently more than 600 diseases characterized as affecting the central nervous
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …

Exosomes from human gingiva‐derived mesenchymal stem cells combined with biodegradable chitin conduits promote rat sciatic nerve regeneration

F Rao, D Zhang, T Fang, C Lu, B Wang… - Stem cells …, 2019 - Wiley Online Library
At present, repair methods for peripheral nerve injury often fail to get satisfactory result.
Although various strategies have been adopted to investigate the microenvironment after …

Strategies for regeneration of components of nervous system: scaffolds, cells and biomolecules

L Tian, MP Prabhakaran… - Regenerative …, 2015 - academic.oup.com
Nerve diseases including acute injury such as peripheral nerve injury (PNI), spinal cord
injury (SCI) and traumatic brain injury (TBI), and chronic disease like neurodegeneration …