[HTML][HTML] Nasal epithelial barrier integrity and tight junctions disruption in allergic rhinitis: overview and pathogenic insights
Allergic rhinitis (AR) is a common disorder affecting up to 40% of the population worldwide
and it usually persists throughout life. Nasal epithelial barrier constitutes the first line of …
and it usually persists throughout life. Nasal epithelial barrier constitutes the first line of …
Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics
C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …
Mechanisms and strategies to enhance penetration during intravesical drug therapy for bladder cancer
P Zhang, G Wu, D Zhang, WF Lai - Journal of Controlled Release, 2023 - Elsevier
Bladder cancer (BCa) is one of the most prevalent cancers worldwide. The effectiveness of
intravesical therapy for bladder cancer, however, is limited due to the short dwell time and …
intravesical therapy for bladder cancer, however, is limited due to the short dwell time and …
Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics
Z Ye, Y Bao, Z Chen, H Ye, Z Feng, Y Li, Y Zeng… - Coordination Chemistry …, 2024 - Elsevier
Cancer is an extremely significant disease that profoundly impacts human survival and
quality of life. Researchers have been searching for effective therapies, among which …
quality of life. Researchers have been searching for effective therapies, among which …
[HTML][HTML] How the innate immune DNA sensing cGAS–STING pathway is involved in autophagy
W Zheng, N Xia, J Zhang, N Chen, F Meurens… - International Journal of …, 2021 - mdpi.com
The cGAS–STING pathway is a key component of the innate immune system and exerts
crucial roles in the detection of cytosolic DNA and invading pathogens. Accumulating …
crucial roles in the detection of cytosolic DNA and invading pathogens. Accumulating …
[HTML][HTML] Connexin channels modulation in pathophysiology and treatment of immune and inflammatory disorders
A Tittarelli - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2021 - Elsevier
Connexin-mediated intercellular communication mechanisms include bidirectional cell-to-
cell coupling by gap junctions and release/influx of molecules by hemichannels. These …
cell coupling by gap junctions and release/influx of molecules by hemichannels. These …
[HTML][HTML] Connexin 43 and sonic hedgehog pathway interplay in glioblastoma cell proliferation and migration
F Torrisi, C Alberghina, D Lo Furno, A Zappalà… - Biology, 2021 - mdpi.com
Simple Summary Glioblastoma is the product of accumulated genetic and epigenetic
alteration where tumor cells support each other through cellular communication …
alteration where tumor cells support each other through cellular communication …
cGAS-STING at the crossroads in cancer therapy
R Wang, A Hussain, Q Guo, M Ma - Critical Reviews in Oncology …, 2023 - Elsevier
DNA is highly immunogenic, both exogenous and endogenous DNA can activate the
pathogen-associated molecular pattern (PAMP) and danger-associated molecular pattern …
pathogen-associated molecular pattern (PAMP) and danger-associated molecular pattern …
Connexin-containing vesicles for drug delivery
MS Hanafy, Z Cui - The AAPS Journal, 2024 - Springer
Connexin is a transmembrane protein present on the cell membrane of most cell types.
Connexins assemble into a hexameric hemichannel known as connexon that pairs with …
Connexins assemble into a hexameric hemichannel known as connexon that pairs with …
Spotlight on liver macrophages for halting liver disease progression and injury
Introduction Over the past two decades, understanding of hepatic macrophage biology has
provided astounding details of their role in the progression and regression of liver diseases …
provided astounding details of their role in the progression and regression of liver diseases …