[HTML][HTML] Canalization and plasticity in psychopathology

RL Carhart-Harris, S Chandaria, DE Erritzoe… - …, 2023 - Elsevier
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …

[HTML][HTML] Association between mystical-type experiences under psychedelics and improvements in well-being or mental health–A comprehensive review of the …

S Kangaslampi - Journal of psychedelic studies, 2023 - akjournals.com
Background and aims Ingestion or administration of classic psychedelics is sometimes
associated with improvements in well-being or mental health. Acute mystical-type …

[HTML][HTML] Co-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences

RJ Zeifman, H Kettner, BA Pagni, A Mallard… - Scientific reports, 2023 - nature.com
Psilocybin and lysergic acid diethylamide (LSD) experiences can range from very positive to
highly challenging (eg, fear, grief, and paranoia). These challenging experiences contribute …

How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change

RJ Zeifman, AC Wagner, CM Monson… - Journal of Affective …, 2023 - Elsevier
Background Psilocybin therapy is receiving attention as a mental health intervention with
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …

Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020

EI Kopra, JA Ferris, AR Winstock… - Journal of …, 2023 - journals.sagepub.com
Background: Growing numbers of people are using psychedelics for personal
psychotherapy outside clinical settings, but research on such use is scarce. Aims: This study …

Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample

VA Nygart, LM Pommerencke… - Journal of …, 2022 - journals.sagepub.com
Background: Over the last two decades, a number of studies have highlighted the potential
of psychedelic therapy. However, questions remain to what extend these results translate to …

[HTML][HTML] Effects of DMT on mental health outcomes in healthy volunteers

C Timmermann, RJ Zeifman, D Erritzoe, DJ Nutt… - Scientific Reports, 2024 - nature.com
Psilocybin, a serotonergic psychedelic, is being increasingly researched in clinical studies
for the treatment of psychiatric disorders. The relatively lengthy duration of oral psilocybin's …

Effects of psilocybin versus escitalopram on rumination and thought suppression in depression

T Barba, S Buehler, H Kettner, C Radu, BG Cunha… - BJPsych Open, 2022 - cambridge.org
BackgroundMajor depressive disorder is often associated with maladaptive coping
strategies, including rumination and thought suppression. AimsTo assess the comparative …

Pattern breaking: a complex systems approach to psychedelic medicine

I Hipólito, J Mago, FE Rosas… - Neuroscience of …, 2023 - academic.oup.com
Recent research has demonstrated the potential of psychedelic therapy for mental health
care. However, the psychological experience underlying its therapeutic effects remains …

Pilot study of single-dose psilocybin for serotonin reuptake inhibitor-resistant body dysmorphic disorder

FR Schneier, J Feusner, MG Wheaton… - Journal of psychiatric …, 2023 - Elsevier
Objective Body dysmorphic disorder (BDD) is an often-severe condition in which individuals
are preoccupied by misperceptions of their appearance as defective or ugly. Only serotonin …