Cardiovascular diseases are the leading cause of death worldwide, among which ischemic
heart disease is the most representative. Myocardial infarction results from occlusion of a …

Fibrosis can occur in a variety of organs such as the heart, lung, liver and kidney, and its
pathological changes are mainly manifested by an increase in fibrous connective tissue and …

Long non-coding (lnc) RNAs, once considered as junk and useless, are now broadly
recognized to have major functions in the cell. LncRNAs are defined as non-coding RNAs of …

As the most prevalent epitranscriptomic modification, N6-methyladenosine (m6A) shows
important roles in a variety of diseases through regulating the processing, stability and …

Fibrosis is a pathological phenomenon characterized by the aberrant accumulation of
extracellular matrix (ECM) in tissues. Fibrosis is a universally age-related disease involving …

Cardiovascular diseases have become the leading cause of death in urban and rural areas.
Myocardial fibrosis is a common pathological manifestation at the adaptive and repair stage …

Chronic tissue injury triggers changes in the cell type and microenvironment at the site of
injury and eventually fibrosis develops. Current research suggests that fibrosis is a highly …

m6A 甲基化修饰非编码RNA 调控病理性心脏重塑的作用 Page 1 3252|中国组织工程研究|第28卷
|第20期|2024年7月 中国组织工程研究 Chinese Journal of Tissue Engineering Research …

Cardiac fibrosis leads to decreased cardiac compliance, impaired systolic and diastolic
function, resulting in heart failure. M6A methylation plays a role in fibrosis development …

In the healing process of myocardial infarction, cardiac fibroblasts are activated and serious
cardiac fibrosis developed, which eventually leads to cardiac remodeling and heart failure …