CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and
mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is …

Prior to 1981, treatment options for invasive fungal infections were limited and associated
with significant toxicities. The introduction of ketoconazole marked the beginning of an era of …

Solid lipid nanoparticles (SLNs) are very potential formulations for topical delivery of
antifungal drugs. Hence, the purpose of this research was to formulate the well-known …

Invasive fungal infections remain a major cause of morbidity and mortality in
immunocompromised patients, and such infections are a substantial burden to healthcare …

Background Guttate psoriasis is common and affects 0.5–2% of individuals in the paediatric
age group. This review aims to familiarize physicians with the clinical manifestations …

The cytochrome P450 enzyme lanosterol 14α-demethylase (LDM) is the target of the azole
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …

Introduction Recurrent vulvovaginal candidiasis (RVVC) affects women worldwide and has
far-reaching implications for a patient's quality of life. For decades, maintenance treatment …

Background Tinea versicolor is a common superficial fungal infection of the skin with various
clinical manifestations. This review aims to familiarize physicians with the clinical features …

Background: Ketoconazole was the first broad-spectrum oral antifungal agent available to
treat systemic and superficial mycoses. Evidence of hepatotoxicity associated with its use …

This narrative review presents a comprehensive overview of the diagnosis and management
of pityriasis versicolor (PV), a common superficial fungal infection caused by the yeast …