Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Although chronic obstructive pulmonary disease (COPD) is a major global health problem
with a rising incidence and morbidity, few pharmacotherapeutic advances have been made …

Rationale: Although the rate of annual decline in FEV1 is one of the most important outcome
measures in chronic obstructive pulmonary disease (COPD), little is known about …

Studies have described individuals with combined pulmonary fibrosis and emphysema
(CPFE), with preserved lung volumes, significant reductions in gas exchange, and high …

Rationale: Microalbuminuria (MAB), a marker of endovascular dysfunction, is a predictor of
cardiovascular events and all-cause mortality in the general population. There is evidence of …

Rationale: Previous studies have shown associations between dust exposure or lung
burden and emphysema in coal miners, although the separate contributions of various …

There is limited knowledge on the relationship between diffusing capacity of the lung for
carbon monoxide (DLCO) and quantitative computed tomography (CT) measures of …

Purpose To implement and assess the performance of three‐dimensional (3D) ultra‐short
echo (UTE) time for evaluating lung tissue density changes induced by gravity dependence …

Objectives To determine the correlation between CT measurements of emphysema or
peripheral airways and airflow obstruction in chronic obstructive pulmonary disease …

A pulmonary ventilation imaging technique based on four-dimensional (4D) computed
tomography (CT) has advantages over existing techniques. However, physiologically …