[HTML][HTML] Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications
M Guo, X Sun, J Chen, T Cai - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …
Cocrystal engineering of pharmaceutical solids: Therapeutic potential and challenges
Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …
molecules in the same crystal lattice that are physically connected by non-ionic and non …
Diffusion and Flux Improvement of Drugs through Complexation
Improving the solubility and permeability of drugs via cocrystallization is an important theme
in crystal engineering with practical applications for the discovery and development of high …
in crystal engineering with practical applications for the discovery and development of high …
[HTML][HTML] Amino acids as the potential co-former for co-crystal development: a review
I Nugrahani, MA Jessica - Molecules, 2021 - mdpi.com
Co-crystals are one of the most popular ways to modify the physicochemical properties of
active pharmaceutical ingredients (API) without changing pharmacological activity through …
active pharmaceutical ingredients (API) without changing pharmacological activity through …
An outlook on permeability escalation through cocrystallization for developing pharmaceuticals with improved biopharmaceutical properties
Permeability of any pharmaceutical is critically significant for its biopharmaceutical profile,
therapeutic activities, and deciding its dosing regimen. Approximately 35% of the marketed …
therapeutic activities, and deciding its dosing regimen. Approximately 35% of the marketed …
Directed Self-Assembly with Gallic Acid Provides First Phenolic Acid Cocrystals for the Antiviral Drug Acyclovir toward Increasing Pharmaceutical Features and …
FZ Bu, YM Yu, M Zhang, CW Yan, ZY Wu… - Crystal Growth & …, 2023 - ACS Publications
To achieve new breakthroughs in the development of synergistic antiviral medication
cocrystals of acyclovir (AYL) with phenolic acids, a cocrystallization-driven strategy for …
cocrystals of acyclovir (AYL) with phenolic acids, a cocrystallization-driven strategy for …
Molecular complexes of drug combinations: a review of cocrystals, salts, coamorphous systems and amorphous solid dispersions
As the advancements in the medical technology and healthcare develop through the years,
combinational therapy has evolved to be an important treatment modality in many disease …
combinational therapy has evolved to be an important treatment modality in many disease …
Directional Self-Assembly of Ofloxacin and Syringic Acid: The First Salt Cocrystal of Ofloxacin with Phenolic Acid Displays Superior In Vitro/Vivo Biopharmaceutical …
SS Meng, YM Yu, FZ Bu, CW Yan, ZY Wu… - Crystal Growth & …, 2022 - ACS Publications
A cocrystallization tactic of double optimization and synergistic enhancement efficacy has
been proposed, aiming at maximizing the benefits of phenolic acid nutriment syringic acid …
been proposed, aiming at maximizing the benefits of phenolic acid nutriment syringic acid …
Two cocrystal polymorphs of palmatine chloride with racemic hesperetin
Y Zhang, Y Li, L Liu, Q Guo, R Sa… - Crystal Growth & …, 2021 - ACS Publications
Two polymorphic cocrystals of palmatine chloride with racemic hesperetin (Form I and Form
II) have been prepared and investigated systematically. Crystal structure analysis reveals …
II) have been prepared and investigated systematically. Crystal structure analysis reveals …
Novel formulations of the antiviral drug favipiravir: Improving permeability and tabletability
X Wang, L Wang, C Yao, G Xie, S Song… - Crystal Growth & …, 2021 - ACS Publications
Recently, favipiravir, as a broad-spectrum antiviral drug, has gain more attention because it
might be a candidate to remedy the coronavirus disease 2019 (COVID-19). To improve its …
might be a candidate to remedy the coronavirus disease 2019 (COVID-19). To improve its …