LPS versus Poly I: C model: comparison of long-term effects of bacterial and viral maternal immune activation on the offspring

M Bao, N Hofsink, T Plösch - American Journal of …, 2022 - journals.physiology.org
A prominent health issue nowadays is the COVID-19 pandemic, which poses acute risks to
human health. However, the long-term health consequences are largely unknown and …

[HTML][HTML] Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the …

RM Woods, JM Lorusso, HG Potter, JC Neill… - Neuroscience & …, 2021 - Elsevier
Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

[PDF][PDF] COVID-19 and pregnancy: clinical outcomes and scientific evidence about vaccination.

A FACCIOLÀ, C Micali, G Visalli… - European Review for …, 2022 - europeanreview.org
Pregnant women and their infants are at high risk to develop a severe COVID-19, with
increased rates of hospitalisation to intensive care units, need for mechanical ventilation and …

[HTML][HTML] The combined effect of weaning stress and immune activation during pig gestation on serum cytokine and analyte concentrations

HE Rymut, LA Rund, CR Bolt, MB Villamil, BR Southey… - Animals, 2021 - mdpi.com
Simple Summary The present study of blood chemical, cytokine and hormone indicators in
male and female pigs offered insights into the combined effects of maternal immune …

[HTML][HTML] Mid-pregnancy poly (I: C) viral mimic disrupts placental ABC transporter expression and leads to long-term offspring motor and cognitive dysfunction

VRS Monteiro, CBV Andrade, HR Gomes… - Scientific Reports, 2022 - nature.com
Limited information is available about the effect of mid-pregnancy viral infections on the
placental expression of efflux transporters and offspring behavior. We hypothesized that …

COVID-19 and developmental origins of health and disease

S Forestieri, R Pintus, MA Marcialis, MC Pintus… - Early human …, 2021 - Elsevier
From the moment of the identification of SARS-CoV-2 as an etiological agent of the severe
clinical pictures of pneumonia that were being slowly observed all over the world, numerous …

[HTML][HTML] Influence of prenatal drug exposure, maternal inflammation, and parental aging on the development of autism spectrum disorder

A Sato, H Kotajima-Murakami, M Tanaka… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) affects reciprocal social interaction and produces abnormal
repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into …

[HTML][HTML] Poly(I:C)-exposed zebrafish shows autism-like behaviors which are ameliorated by fabp2 gene knockout

J Wu, X Lin, D Wu, B Yan, M Bao, P Zheng… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders
mainly representing impaired social communication. The etiology of ASD includes genetic …

[HTML][HTML] Biochemistry and immune biomarkers indicate interacting effects of pre-and postnatal stressors in pigs across sexes

HE Rymut, LA Rund, CR Bolt, MB Villamil, DE Bender… - Animals, 2021 - mdpi.com
Simple Summary This study evaluated the effects of MIA elicited by porcine reproductive and
respiratory syndrome virus and postnatal metabolic or immune stressors on chemical and …

Maternal immune activation and dietary soy isoflavone supplementation influence pig immune function but not muscle fiber formation

EE Bryan, X Chen, BN Smith, RN Dilger… - Journal of animal …, 2022 - academic.oup.com
The goals of this study were to determine the impact of maternal PRRSV infection on
offspring muscle and immune development and the potential of dietary soy isoflavones to …