DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …

DNA methylation is a highly regulated process that has a critical role in human development
and homeostatic control of the cell. The number of genes affected by anomalous DNA …

Epigenetics is the study of heritable and stable changes in gene expression that occur
through alterations in the chromosome rather than in the DNA sequence. Despite not directly …

Objective Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney tumor
characterized by the highest mortality rate of the genitourinary cancers, and, therefore, new …

Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …

Cancer progression is a multifaceted process that entails several stages and demands the
persistent expression or activation of transcription factors (TFs) to facilitate growth and …

Disruption in DNA methylation processes can lead to alteration in gene expression and
function that would ultimately result in malignant transformation. In this way, studies have …

Simple Summary Cancer metastasis is considered to be one of the most significant causes
of cancer morbidity, accounting for up to 90% of cancer deaths. The accurate identification of …

Background: Dietary intake of antioxidants such as vitamins C and E protect against
oxidative stress, and may also be associated with altered DNA methylation patterns …

Breast cancer remains the most commonly diagnosed cancer worldwide and exhibits a poor
prognosis. The induction of genetic changes deregulates several genes that increase the …