[HTML][HTML] Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

[HTML][HTML] Intertwined relationship of mitochondrial metabolism, gut microbiome and exercise potential

S Imdad, W Lim, JH Kim, C Kang - International Journal of Molecular …, 2022 - mdpi.com
The microbiome has emerged as a key player contributing significantly to the human
physiology over the past decades. The potential microbial niche is largely unexplored in the …

[HTML][HTML] Prevotellaceae produces butyrate to alleviate PD-1/PD-L1 inhibitor-related cardiotoxicity via PPARα-CYP4X1 axis in colonic macrophages

Y Chen, Y Liu, Y Wang, X Chen, C Wang… - Journal of Experimental …, 2022 - Springer
Background Immune checkpoint inhibitor-related cardiotoxicity is one of the most lethal
adverse effects, and thus, the identification of underlying mechanisms for developing …

[HTML][HTML] Mitochondria as novel mediators linking gut microbiota to atherosclerosis that is ameliorated by herbal medicine: A review

Y Li, S Yang, X Jin, D Li, J Lu, X Wang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the main cause of cardiovascular disease (CVD) and is
characterized by endothelial damage, lipid deposition, and chronic inflammation. Gut …

[HTML][HTML] The accumulation and molecular effects of trimethylamine N-oxide on metabolic tissues: It's not all bad

ES Krueger, TS Lloyd, JS Tessem - Nutrients, 2021 - mdpi.com
Since elevated serum levels of trimethylamine N-oxide (TMAO) were first associated with
increased risk of cardiovascular disease (CVD), TMAO research among chronic diseases …

Gut-microbiota derived bioactive metabolites and their functions in host physiology

N Debnath, R Kumar, A Kumar, PK Mehta… - Biotechnology and …, 2021 - Taylor & Francis
Every individual harbours a complex, diverse and mutualistic microbial flora in their intestine
and over the time it became an integral part of the body, affecting a plethora of activities of …

[HTML][HTML] Intestinal flora: a potential new regulator of cardiovascular disease

Y Zou, X Song, N Liu, W Sun, B Liu - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Although substantial progress has been made in reducing the burden of the disease by
preventing the risk factors of cardiovascular disease (CVD), potential risk factors still exist …

[HTML][HTML] The potential mechanism of gut microbiota-microbial metabolites-mitochondrial axis in progression of diabetic kidney disease

L Ma, L Zhang, J Li, X Zhang, Y Xie, X Li, B Yang… - Molecular …, 2023 - Springer
Diabetic kidney disease (DKD), has become the main cause of end-stage renal disease
(ESRD) worldwide. Lately, it has been shown that the onset and advancement of DKD are …

[HTML][HTML] Protective effects of meldonium in experimental models of cardiovascular complications with a potential application in COVID-19

R Vilskersts, D Kigitovica, S Korzh, M Videja… - International Journal of …, 2021 - mdpi.com
Right ventricular (RV) and left ventricular (LV) dysfunction is common in a significant number
of hospitalized coronavirus disease 2019 (COVID-19) patients. This study was conducted to …

[HTML][HTML] Microbial metabolites and heart failure: Friends or enemies?

X Lu, J Liu, B Zhou, S Wang, Z Liu, F Mei… - Frontiers in …, 2022 - frontiersin.org
Heart failure (HF), a global health issue characterized by structural or functional cardiac
dysfunction, which was found to be associated with the gut microbiome recently. Although …