Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China
L Yang, Z Wang - European Journal of Medicinal Chemistry, 2023 - Elsevier
The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …
The therapeutic potential of natural dietary flavonoids against SARS-CoV-2 infection
Z Wang, L Yang - Nutrients, 2023 - mdpi.com
The exploration of non-toxic and cost-effective dietary components, such as epigallocatechin
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …
[HTML][HTML] Serial viral load analysis by DDPCR to evaluate FNC efficacy and safety in the treatment of mild cases of COVID-19
RM da Silva, P Gebe Abreu Cabral… - Frontiers in …, 2023 - frontiersin.org
Introduction: The SARS-CoV-2 outbreak has threatened the human population globally as
the numbers of reinfection cases even after large-scale vaccination. Trials have been carried …
the numbers of reinfection cases even after large-scale vaccination. Trials have been carried …
Deuremidevir and Simnotrelvir–Ritonavir for the Treatment of COVID-19
KW Zhu - ACS Pharmacology & Translational Science, 2023 - ACS Publications
Deuremidevir hydrobromide tablets and simnotrelvir tablets/ritonavir tablets (co-packaged)
were approved by the Chinese National Medical Products Administration for the treatment of …
were approved by the Chinese National Medical Products Administration for the treatment of …
Efficacy of remdesivir and neutralizing monoclonal antibodies in monotherapy or combination therapy in reducing the risk of disease progression in elderly or …
DF Bavaro, L Diella, A Belati, G Metrangolo… - Viruses, 2023 - mdpi.com
Introduction: Remdesivir (REM) and monoclonal antibodies (mAbs) could alleviate severe
COVID-19 in at-risk outpatients. However, data on their use in hospitalized patients …
COVID-19 in at-risk outpatients. However, data on their use in hospitalized patients …
Synergistic Activity of Remdesivir–Nirmatrelvir Combination on a SARS-CoV-2 In Vitro Model and a Case Report
A Gidari, S Sabbatini, E Schiaroli, S Bastianelli… - Viruses, 2023 - mdpi.com
Background: This study aims to investigate the activity of the remdesivir–nirmatrelvir
combination against Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and …
combination against Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and …
Ursodeoxycholic acid does not improve COVID-19 outcome in hospitalized patients
Ursodeoxycholic acid (UDCA) was demonstrated to reduce susceptibility to SARS-CoV-2
infection in vitro and improve infection course in chronic liver diseases. However, real-life …
infection in vitro and improve infection course in chronic liver diseases. However, real-life …
Effectiveness of oral nirmatrelvir/ritonavir vs. intravenous three-day remdesivir in preventing progression to severe COVID-19: a single-center, prospective …
Background: Nirmatrelvir/ritonavir (NMV/r) and three-day course remdesivir (3RDV) have
been approved as early treatments for COVID-19 outpatients not requiring supplemental …
been approved as early treatments for COVID-19 outpatients not requiring supplemental …
Traditional Tibetan medicine to fight against COVID-19: Basic theory and therapeutic drugs
K Zhang, L Wang, J Peng, K Sangji, Y Luo… - Frontiers in …, 2023 - frontiersin.org
The Coronavirus Diseases 2019 (COVID-19) has been rapidly spreading globally and has
caused severe harm to the health of people and a substantial social burden. In response to …
caused severe harm to the health of people and a substantial social burden. In response to …
An Overview on Anti-COVID-19 Drug Achievements and Challenges Ahead
M Valipour, H Irannejad, H Keyvani - ACS Pharmacology & …, 2023 - ACS Publications
The appearance of several coronavirus pandemics/epidemics during the last two decades
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …