Lactoferrin (LF) is a naturally present iron-binding globulin with the structural properties of
an N-lobe strongly positively charged terminus and a cage-like structure of nano self …

Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …

The poor efficiency and drastic adverse effects of current cancer therapies entail a radical
shift in treatment paradigms, which require developing cutting-edge therapeutics in …

Reperfusion injury is one of the major causes of disability and death caused by ischemic
stroke, and drug development focuses mainly on single neuron protection. However …

Introduction Brain diseases including brain tumor, Alzheimer's disease, Parkinson's disease,
etc. are difficult to treat. The blood–brain barrier (BBB) is a major obstacle for drug delivery …

Brain diseases, including neurodegenerative diseases, acute ischemic stroke and brain
tumors, have become a major health problem and a huge burden on society with high …

With the intrinsic ability to cross the blood-brain barrier, small extracellular vesicles (sEVs)
hold promise as endogenous brain-targeted drug delivery nano-platforms for glioblastoma …

Gliomas are highly invasive and are the most common type of primary malignant brain
tumor. The routine treatments for glioma include surgical resection, radiotherapy, and …

Glioblastoma (GBM) is one of the most malignant tumors of the central nervous system and
has a poor prognosis. GBM cells are highly sensitive to ferroptosis and heat, suggesting …

As the most common primary tumour of the central nervous system, gliomas have a high
recurrence rate after surgical resection and are resistant to chemotherapy, particularly high …