[HTML][HTML] Transcriptome analysis reveals the neuro-immune interactions in duck Tembusu virus-infected brain

J Zhang, Y Huang, L Li, J Dong, M Liao… - International Journal of …, 2020 - mdpi.com
The duck Tembusu virus (DTMUV) is a mosquito-borne flavivirus. It causes severe
symptoms of egg-drop, as well as neurological symptoms and brain damage in ducks …

WNT5B promotes vascular smooth muscle cell dedifferentiation via mitochondrial dynamics regulation in chronic thromboembolic pulmonary hypertension

F Wang, Y Zhen, C Si, C Wang, L Pan… - Journal of Cellular …, 2022 - Wiley Online Library
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by proliferative
vascular remodeling. Abnormal vascular smooth muscle cell (VSMC) phenotype switching is …

Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model

SJ Miller, JC Glatzer, Y Hsieh… - Journal of …, 2018 - Taylor & Francis
Astroglia are the most abundant glia cell in the central nervous system, playing essential
roles in maintaining homeostasis. Key functions of astroglia include, but are not limited to …

LiCl attenuates impaired learning and memory of APP/PS1 mice, which in mechanism involves α7 nAChRs and Wnt/β‐catenin pathway

J Xiang, LY Ran, XX Zeng, WW He, Y Xu… - Journal of Cellular …, 2021 - Wiley Online Library
We examined the mechanism by which lithium chloride (LiCl) attenuates the impaired
learning capability and memory function of dual‐transgenic APP/PS1 mice. Six‐or 12‐month …

Revealing clusters of connected pathways through multisource data integration in huntington's disease and spastic ataxia

AC Kakouri, CC Christodoulou… - IEEE journal of …, 2018 - ieeexplore.ieee.org
The advancement of scientific and medical research over the past years has generated a
wealth of experimental data from multiple technologies, including genomics, transcriptomics …

Dimethyl fumarate mitigates tauopathy in Aβ-induced neuroblastoma SH-SY5Y cells

MS Rajput, NP Nirmal, D Rathore, R Dahima - Neurochemical Research, 2020 - Springer
Alzheimer's disease pathogenesis is measured by two key hallmarks viz extracellular senile
plaques composed of insoluble amyloid beta (Aβ) and neurofibrillary tangles composed of …

Identification of dysregulated genes and pathways of different brain regions in Alzheimer's disease

Y Wang, Z Wang - International Journal of Neuroscience, 2020 - Taylor & Francis
Background: Alzheimer's disease (AD) is a degenerative neurologic disease. The study
aimed to identify the key differentially expressed genes (DEGs) and pathways in AD …

[HTML][HTML] FMP-6-S4 impeded Aβ42 induced SH-SY5Y cell injury by targeting cyclophilin D

P Gao, S Li, Y Wang, F Wu, C Jin, D Zhao… - Journal of Functional …, 2024 - Elsevier
Amyloid β (Aβ) is pivotal in the progression of Alzheimer's disease (AD) by inducing neuron
damage. Recent evidences implied that the formation of mitochondrial permeability …

[HTML][HTML] Alteration of Golgi structure by stress: a link to neurodegeneration?

EA Alvarez-Miranda, M Sinnl, H Farhan - Frontiers in neuroscience, 2015 - frontiersin.org
The Golgi apparatus is well-known for its role as a sorting station in the secretory pathway as
well as for its role in regulating post-translational protein modification. Another role for the …

[HTML][HTML] MicroRNA changes of bone marrow-derived mesenchymal stem cells differentiated into neuronal-like cells by Schwann cell-conditioned medium

ZJ Wei, BY Fan, Y Liu, H Ding, HS Tang… - Neural Regeneration …, 2019 - journals.lww.com
Bone marrow-derived mesenchymal stem cells differentiate into neurons under the induction
of Schwann cells. However, key microRNAs and related pathways for differentiation remain …