[HTML][HTML] Wnt5a protects motor neurons in amyotrophic lateral sclerosis by regulating the Wnt/Ca2+ signaling pathway

J Liu, F Zhou, Y Chen, Y Guan, F Meng… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: We aimed to detect the expression profile of downstream signaling molecules of
non-canonical Wnt pathway in SOD1 G93A transgenic mice (ALS mice) and SOD1 G93A …

Anti-Aging Effect of Siraitia grosuenorii by Enhancement of Hematopoietic Stem Cell Function

L Bai, G Shi, Y Yang, W Chen… - The American Journal of …, 2016 - World Scientific
Anti-aging has always been a popular topic, and there are many claims about the existence
of factors that can slow, stop, or even reverse the aging process. Siraitia grosuenorii, a local …

Emerging roles of signal transduction pathways in neurodegenerative diseases. Hunting new possible therapeutic molecular targets

VR Lo Vasco - OBM Geriatrics, 2023 - iris.unimore.it
Illnesses following the degeneration of the nervous system can occur due to aging or
genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of …

Signaling Pathways in Neurodegeneration

D Verma, A Sen, P Sahoo, M Mutsuddi… - Altered Metabolism: A …, 2024 - Springer
Neurodegeneration is the progressive loss of specific subsets of neurons present in the
central nervous system leading to cognitive disability, including dementia …

Fortified S‐Allyl L‐Cysteine: Animal Safety, Effect on Retinal Ischemia, and Role of Wnt in the Underlying Therapeutic Mechanism

WWJ Chao, YK Chen, HWH Chao… - Evidence‐Based …, 2020 - Wiley Online Library
Purpose. Retinal ischemia is a medical condition associated with numerous retinal vascular
disorders, such as age‐related macular degeneration, glaucoma, and diabetic retinopathy …

Investigation of the lipid-lowering effect of vitamin C through GSK-3β/β-catenin signaling in zebrafish

D Liu, H Yu, Q Pang, X Zhang - Frontiers in Physiology, 2018 - frontiersin.org
Vitamin C (VC) is an essential nutrient for most fish species because of the absence of l-
gulonolactone oxidase in the bodies of fish. VC plays a significant role in maintaining the …

Low-dose exposure to malathion and radiation culminates in the dysregulation of multiple neuronal processes instigating neurotoxicity and activation of …

KN Rekha, BS Venkidesh, S Nayak, D Reghunathan… - bioRxiv, 2023 - biorxiv.org
Neurodegenerative disorders are a debilitating and persistent threat to the global elderly
population carrying grim outcomes. Their genesis is often multifactorial, with a history of …

骨髓间充质干细胞由许旺细胞条件培养基诱导分化为神经元样细胞中miRNA 变化的分析

ZJ Wei, BY Fan, Y Liu, H Ding, HS Tang… - 中国神经再生研究 …, 2019 - sjzsyj.com.cn
研究已证实在许旺细胞诱导条件下, 骨髓间充质干细胞能够向神经元方向分化,
但分化过程中的关键miRNA 及相关通路还不清楚. 为此, 实验筛选和鉴定许旺细胞条件培养基 …

Antioxidant dihydrolipolic acid protects against aluminum-induced toxicity in Alzheimer's model

S SANAJOU, A Yirün, G Demirel, DA Cakir, G Sahin… - 2023 - researchsquare.com
Dihydrolipoic acid (DHLA) is a natural antioxidant that is recognized as being useful in
combating metal toxicity and oxidative stress. It can protect cells from environmental …

Characterization of early Alzheimer's-like pathological alterations in non-human primates with aging: a pilot study

H Jester, S Gosrani, H Ding, X Zhou, MC Ko, T Ma - bioRxiv, 2021 - biorxiv.org
Sporadic or late onset Alzheimer's disease (LOAD) is a multifactorial neurodegenerative
disease with aging the most known risk factor. Non-human primates (NHPs) may serve as …