[PDF][PDF] Differentielle Genexpressionsanalysen aus Muskeleinzelfasern bei mitochondrialen Myopathien

K Olszewski - 2018 - edoc.ub.uni-muenchen.de
Die Komplexität mitochondrialer Krankheitsbilder erklärt sich aus den besonderen
genetischen Eigenschaften der Mitochondrien. Daher ist zum Verständnis der …

WNT vampirization by glioblastoma leads to tumor growth and neurodegeneration

M Portela-Esteban, V Venkataramani, N Fahey-Lozano… - 2018 - opal.latrobe.edu.au
SummaryGlioblastoma (GB) is the most lethal brain tumor due to its high proliferation,
aggressiveness, infiltration capacity and resilience to current treatments. Activation of the …

Demencia frontotemporal lobar asociada al déficit de progranulina: búsqueda de nuevas dianas terapéuticas y modelos experimentales para su desarrollo preclínico

A Encarnación Salmerón - 2018 - docta.ucm.es
Frontotemporal Lobar Degeneration (FTLD) describes a spectrum of clinically,
pathologically and genetically heterogeneous disease with a common feature, the relatively …

[PDF][PDF] Astroglia heterogeneity in the adult central nervous system in health and disease

SJ Miller - 2018 - jscholarship.library.jhu.edu
Astroglia are essential for the homeostasis and maintenance of the central nervous system
(CNS). They are the most abundant neuroglia cell type and display a vast array of roles such …

[引用][C] Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis

Are caffeine's effects on neuronal calcium levels due to the caffeine metabolite, paraxanthine?

KJ Hartsuyker - 2017 - digitalcommons.humboldt.edu
Caffeine has diverse effects on neurons including, potentially, protection against Parkinson's-
related neurodegeneration. Caffeine may protect neurons from damage by limiting …

Wnt signaling prevents the A Beta Oligomer-induced mitochondrial permeability transition pore opening preserving mitochondrial structure in hippocampal neurons

P Cisternas, MS Arrazola, E Ramos-Fernández… - 2017 - repositorioacademico.uda.cl
Alzheimer's disease (AD) is a neurodegenerative disorder mainly known for synaptic
impairment and neuronal cell loss, affecting memory processes. Beside these damages …

Structured clustering representations and methods

A Heilbut - 2016 - search.proquest.com
Rather than designing focused experiments to test individual hypotheses, scientists now
commonly acquire measurements using massively parallel techniques, for post hoc …

[PDF][PDF] Research Article Wnt5a Increases the Glycolytic Rate and the Activity of the Pentose Phosphate Pathway in Cortical Neurons

P Cisternas, P Salazar, C Silva-Álvarez, LF Barros… - 2016 - academia.edu
In the last few years, several reports have proposed that Wnt signaling is a general
metabolic regulator, suggesting a role for this pathway in the control of metabolic flux. Wnt …

[PDF][PDF] A novel role for Adenomatous Polyposis Coli protein in the transport of mitochondria

KM Mills - 2015 - Citeseer
Abstract Adenomatous Polyposis Coli (APC) is a multifunctional tumour suppressor protein
and a negative regulator of the β-catenin Wnt signalling pathway. APC also contributes to …